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Debt - (Tables)
9 Months Ended
Sep. 30, 2024
Debt Instrument, Redemption [Line Items]  
Summary of liability for sale of future royalties

    

Nine Months Ended September 30, 

Liability for sale of future royalties- (current and noncurrent)

2024

Beginning balance as of December 31, 2023

$

1,814,097

Less: Non-cash royalty revenue payable to Royalty Pharma

(128,877)

Plus: Non-cash interest expense recognized

155,039

Plus: Cash received from Royalty Pharma

241,792

Ending balance

$

2,082,051

Effective interest rate as of September 30, 2024

 

9.9%

1.50% Convertible senior notes due 2026  
Debt Instrument, Redemption [Line Items]  
Summary of convertible notes

    

September 30, 2024

December 31, 2023

Principal

$

287,500

$

287,500

Less: Debt issuance costs

 

(2,394)

 

(3,287)

Net carrying amount

$

285,106

$

284,213

Summary of interest expense recognized related to the Convertible Notes

Three Months Ended September 30, 

Nine Months Ended September 30, 

    

2024

2023

    

2024

2023

Contractual interest expense

$

1,081

$

1,080

$

3,224

$

3,215

Amortization of debt issuance costs

 

300

294

891

872

Total

$

1,381

$

1,374

$

4,115

$

4,087

Effective interest rate

 

1.9

%

1.9

%

1.9

%

1.9

%

Blackstone Credit Agreement  
Debt Instrument, Redemption [Line Items]  
Schedule of credit agreement

    

September 30, 2024

December 31, 2023

Principal

$

$

300,000

Less: Debt issuance costs

 

Repayment of senior secured term loan

(300,000)

Net carrying amount

$

$

Summary of interest expense recognized related to debt

Three Months Ended

Nine Months Ended

September 30, 

September 30, 

2024

2023

2024

2023

Contractual interest expense

$

$

9,554

$

$

28,087

Amortization of debt issuance costs

 

 

280

702

Total

$

$

9,834

$

$

28,789

Effective interest rate

%

13.1

%

%

13.1

%