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Intangible assets and goodwill - (Tables)
9 Months Ended
Sep. 30, 2024
Goodwill and Intangible Assets Disclosure [Abstract]  
Schedule of definite lived intangible assets

Ending Balance at

Foreign

Ending Balance at

Definite-lived

December 31,

currency

September 30,

intangibles assets, gross

    

2023

    

Additions

    

translation

    

2024

Emflaza

$

527,417

$

$

$

527,417

Waylivra

10,218

2,732

183

13,133

Tegsedi

13,322

5,269

253

18,844

Upstaza

89,550

89,550

Total definite-lived intangibles, gross

$

640,507

$

8,001

$

436

$

648,944

Ending Balance at

Foreign

Ending Balance at

Definite-lived

December 31,

currency

September 30,

intangibles assets, accumulated amortization

    

2023

    

Amortization

    

translation

    

2024

Emflaza

$

(478,618)

$

(48,799)

$

$

(527,417)

Waylivra

(3,965)

(1,187)

(63)

(5,215)

Tegsedi

(3,311)

(1,847)

(72)

(5,230)

Upstaza

(10,882)

(5,598)

(16,480)

Total definite-lived intangibles, accumulated amortization

$

(496,776)

$

(57,431)

$

(135)

$

(554,342)

Total definite-lived intangibles, net

$

94,602

Schedule of estimated future amortization of intangible assets

    

As of September 30, 2024

2024

$

3,043

2025

 

12,160

2026

 

12,160

2027

 

12,160

2028 and thereafter

 

55,079

Total

$

94,602

Schedule of indefinite lived intangible assets

Ending Balance at

Ending Balance at

Indefinite-lived

December 31,

September 30,

intangibles assets

    

2023

    

Additions

    

Impairment

    

2024

    

Upstaza

$

235,766

$

$

$

235,766

Total indefinite-lived intangibles

$

235,766

$

$

$

235,766

Total intangible assets, net

$

330,368