XML 44 R33.htm IDEA: XBRL DOCUMENT v3.24.3
Summary of significant accounting policies - Narrative (Details)
$ in Thousands
 1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Dec. 22, 2017
Jun. 30, 2022
USD ($)
Sep. 30, 2024
USD ($)
country
Sep. 30, 2023
USD ($)
country
Sep. 30, 2024
USD ($)
country
Sep. 30, 2023
USD ($)
country
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2019
USD ($)
Jul. 31, 2025
USD ($)
Jun. 30, 2024
USD ($)
Dec. 31, 2018
USD ($)
New Accounting Pronouncements or Change in Accounting Principle [Line Items]                        
Allowance for credit loss     $ 0 $ 0 $ 0 $ 0            
Increase in allowance for credit losses     0 0 0 0            
Allowance for doubtful accounts receivable     1,300   1,300     $ 1,200        
Bad debt expense     700 400 500 700            
Revenue     196,786 $ 196,576 593,608 630,766            
Income taxes                        
Federal income tax statutory rate 21.00%                      
Deferred tax benefit         2 $ 50,909   $ 46,900        
Forecast                        
Income taxes                        
Increase in current taxable income resulting from the elimination of current deduction of qualifying R&D costs under Section 174.             $ 121,000          
Agilis                        
Income taxes                        
Deferred tax liability                       $ 122,000
Deposits and other assets                        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]                        
Bank guarantee denominated in foreign currency     $ 700   $ 700              
Hopewell Campus                        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]                        
Letters of credit                   $ 3,000 $ 5,000  
Period after which letter of credit may be reduced if lease is not in default                 5 years      
Hopewell Campus | Minimum                        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]                        
Term for letter of credit (in years)                 5 years      
Hopewell Campus | Deposits and other assets                        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]                        
Letters of credit                 $ 7,500      
Hopewell Campus | Fifth Anniversary                        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]                        
Letters of credit                 $ 3,800      
Warren Premises                        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]                        
Period after which letter of credit may be reduced if lease is not in default   5 years                    
Warren Premises | Deposits and other assets                        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]                        
Letters of credit   $ 8,100                    
Warren Premises | Fifth Anniversary                        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]                        
Letters of credit   $ 4,100                    
Net product revenue | Geographic concentration risk                        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]                        
Number of countries exceeding 10% of net product sales | country     2 1 3 3            
Percentage of net product sales threshold     10.00% 10.00% 10.00% 10.00%            
Net product revenue | Geographic concentration risk | Non-US                        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]                        
Revenue     $ 83,500 $ 76,600 $ 289,500 $ 318,500            
Net product revenue | Geographic concentration risk | Russia                        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]                        
Revenue         55,700 69,000            
Net product revenue | Geographic concentration risk | Brazil                        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]                        
Revenue     29,200   68,300 52,500            
Net product revenue | Geographic concentration risk | United States                        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]                        
Revenue     $ 51,900 $ 67,400 $ 156,700 $ 187,700            
Net product revenue | Customer concentration risk                        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]                        
Percentage of net product sales threshold     10.00% 10.00% 10.00% 10.00%            
Product                        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]                        
Revenue     $ 135,421 $ 144,038 $ 446,245 $ 506,187            
Emflaza | Net product revenue | Geographic concentration risk | United States                        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]                        
Revenue     51,900 67,400 156,700 187,700            
Translarna | Net product revenue | Geographic concentration risk | Non-US                        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]                        
Revenue     $ 72,300 $ 69,000 $ 246,200 $ 280,600