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Stock award plan - Stock Option Activity (Details) - Stock option - USD ($)
$ / shares in Units, $ in Thousands
 9 Months Ended
Sep. 30, 2024
Number of options  
Outstanding at the beginning of the period (in shares) 9,600,399
Granted (in shares) 934,735
Exercised (in shares) (211,693)
Forfeited/Cancelled (in shares) (1,149,981)
Outstanding at the end of the period (in shares) 9,173,460
Vested or Expected to vest at the end of the period (in shares) 1,746,884
Exercisable at the end of the period (in shares) 7,254,847
Weighted- average exercise price  
Outstanding at the beginning of the period (in dollars per share) $ 43.59
Granted (in dollars per share) 26.13
Exercised (in dollars per share) 22.41
Forfeited/Cancelled (in dollars per share) 45.86
Outstanding at the end of the period (in dollars per share) 42.01
Vested or Expected to vest at the end of the period (in dollars per share) 35.85
Exercisable at the end of the period (in dollars per share) $ 43.74
Weighted- average remaining contractual term  
Outstanding at the end of the period 5 years 7 months 20 days
Vested or Expected to vest at the end of the period 8 years 5 months 12 days
Exercisable at the end of the period 4 years 10 months 20 days
Aggregate intrinsic value (in thousands)  
Outstanding at the end of the period (in dollars) $ 30,906
Vested or Expected to vest at the end of the period (in dollars) 9,289
Exercisable at the end of the period (in dollars) $ 20,420