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Stock award plan - Share-based compensation expense (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2024	Sep. 30, 2023	Sep. 30, 2024	Sep. 30, 2023
Stock option plan
Share-based compensation expense	$ 19,755	$ 26,942	$ 57,376	$ 85,128
Unrecognized compensation cost	117,800		$ 117,800
Weighted average remaining service period for recognition of unrecognized compensation cost			2 years 3 months 18 days
Research and development
Stock option plan
Share-based compensation expense	9,416	13,986	$ 27,810	44,828
Selling, general and administrative
Stock option plan
Share-based compensation expense	$ 10,339	$ 12,956	$ 29,566	$ 40,300

X

- Definition

Amount of expense for award under share-based payment arrangement. Excludes amount capitalized.

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Amount of cost not yet recognized for nonvested award under share-based payment arrangement.

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