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Revenue recognition - Net Product Sales (Details) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2024 USD ($) segment Distributor country	Sep. 30, 2023 USD ($) segment country Distributor	Sep. 30, 2024 USD ($) segment Distributor country	Sep. 30, 2023 USD ($) Distributor country segment	Dec. 31, 2023 USD ($)
Revenue recognition
Number of operating segments | segment	1	1	1	1
Revenue	$ 196,786	$ 196,576	$ 593,608	$ 630,766
Net product revenue | Geographic concentration risk
Revenue recognition
Number of countries exceeding 10% of net product sales | country	2	1	3	3
Percentage of net product sales threshold	10.00%	10.00%	10.00%	10.00%
Net product revenue | Geographic concentration risk | United States
Revenue recognition
Revenue	$ 51,900	$ 67,400	$ 156,700	$ 187,700
Net product revenue | Geographic concentration risk | Non-US
Revenue recognition
Revenue	83,500	$ 76,600	289,500	318,500
Net product revenue | Geographic concentration risk | Russia
Revenue recognition
Revenue			55,700	69,000
Net product revenue | Geographic concentration risk | Brazil
Revenue recognition
Revenue	$ 29,200		$ 68,300	$ 52,500
Net product revenue | Customer concentration risk
Revenue recognition
Number of distributors | Distributor	2	3	2	2
Percentage of net product sales threshold	10.00%	10.00%	10.00%	10.00%
Product
Revenue recognition
Revenue	$ 135,421	$ 144,038	$ 446,245	$ 506,187
Contract with customer, liability	0		0		$ 0
Emflaza | Net product revenue | Geographic concentration risk | United States
Revenue recognition
Revenue	51,900	67,400	156,700	187,700
Translarna | Net product revenue | Geographic concentration risk | Non-US
Revenue recognition
Revenue	$ 72,300	$ 69,000	$ 246,200	$ 280,600

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