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Revenue recognition - Collaboration and Royalty Revenue (Details)	3 Months Ended		9 Months Ended
	Sep. 30, 2024 USD ($)	Sep. 30, 2023 USD ($)	Sep. 30, 2024 USD ($) product	Sep. 30, 2023 USD ($)	Nov. 30, 2011 USD ($)
Revenue recognition
Number of approved products | product			2
Revenue	$ 196,786,000	$ 196,576,000	$ 593,608,000	$ 630,766,000
Collaboration revenue
Revenue recognition
Revenue				6,000
Royalty revenue
Revenue recognition
Revenue	61,365,000	50,173,000	$ 145,702,000	117,857,000
SMA License Agreement
Revenue recognition
Number of approved products | product			1
SMA License Agreement | Collaboration revenue
Revenue recognition
Revenue	0		$ 0
SMA License Agreement | Royalty revenue
Revenue recognition
Revenue	61,400,000	$ 50,200,000	145,700,000	$ 117,900,000
Research And Development Event Milestones | SMA License Agreement
Revenue recognition
Remaining potential milestones that can be achieved	0		0
Sales Milestones | SMA License Agreement
Revenue recognition
Remaining potential milestones that can be achieved	$ 150,000,000.0		$ 150,000,000.0
Maximum | Research And Development Event Milestones | SMA License Agreement
Revenue recognition
Remaining potential milestones that can be achieved					$ 135,000,000.0
Maximum | Sales Milestones | SMA License Agreement
Revenue recognition
Remaining potential milestones that can be achieved					$ 325,000,000.0

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