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Accounts payable and accrued expenses
12 Months Ended
Dec. 31, 2024
Payables and Accruals [Abstract]  
Accounts payable and accrued expenses

6. Accounts payable and accrued expenses

Accounts payable and accrued expenses at December 31, 2024 and 2023 consist of the following:

December 31, 

2024

    

2023

Employee compensation, benefits, and related accruals

$

61,575

$

62,643

Income tax payable

4,701

Consulting and contracted research

 

19,909

 

27,500

Sales allowance

 

58,644

 

77,176

Sales rebates

 

101,613

 

131,334

Royalties

8,953

74,111

Accounts payable

 

17,274

 

6,045

Milestone payable

11,025

2,500

Other

 

20,598

 

10,674

Total

$

304,292

$

391,983

As of December 31, 2024 and December 31, 2023, there were $0.1 million and $9.0 million, respectively, of accrued restructuring costs included above within employee compensation, benefits, and related accruals from a reduction in

workforce in the year ended December 31, 2023 in connection with the Company’s strategic pipeline prioritization and discontinuation of its preclinical and early research programs in its gene therapy platform.