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Debt - (Tables)

12 Months Ended

Dec. 31, 2024

Debt Instrument, Redemption [Line Items]

Summary of liability for sale of future royalties

The following table shows the activity within the “liability for sale of future royalties- current” and “liability for sale of future royalties- noncurrent” accounts for the year ended December 31, 2024:

​

​	​	​	​	​
​		Year Ended December 31,		​
Liability for sale of future royalties- (current and noncurrent)	​	2024		​
Beginning balance as of December 31, 2023	​	$	1,814,097	​
Less: Non-cash royalty revenue payable to Royalty Pharma	​	​	(181,507)	​
Plus: Non-cash interest expense recognized	​	​	207,394	​
Plus: Cash received from Royalty Pharma	​	​	241,792	​
Ending balance	​	$	2,081,776	​
Effective interest rate as of December 31, 2024	​		9.8%	​

​

1.50% Convertible senior notes due 2026

Debt Instrument, Redemption [Line Items]

Summary of convertible notes

The 2026 Convertible Notes consist of the following:

​

​	​	​	​	​	​	​
​	​	​	Year ended  December 31,
​	​	2024		​	​	2023
Principal	​	$	287,500	​	$	287,500
Less: Debt issuance costs	​		(2,088)	​	​	(3,287)
Net carrying amount	​	$	285,412	​	$	284,213

Summary of interest expense recognized related to debt

The following table sets forth total interest expense recognized related to the 2026 Convertible Notes:

​

​	​	​	​	​	​	​	​	​
​	​	​	December 31,					​
​		​	2024		​	2023		​
Contractual interest expense	​	​	$	4,319	​	$	4,305	​
Amortization of debt issuance costs	​	​		1,198	​	​	1,171	​
Total	​	​	$	5,517	​	$	5,476	​
Effective interest rate	​	​		1.9	%	​	1.9	%

​

Blackstone Credit Agreement

Debt Instrument, Redemption [Line Items]

Schedule of credit agreement

The Blackstone Credit Agreement consisted of the following:

​

​	​	​	​	​	​	​
​		December 31, 2024		​	December 31, 2023
Principal	​	$	—	​	$	300,000
Less: Debt issuance costs	​		—	​	​	—
Repayment of senior secured term loan	​	​	—	​	​	(300,000)
Net carrying amount	​	$	—	​	$	—

Summary of interest expense recognized related to debt

The following table sets forth total interest expense recognized related to the Blackstone Credit Agreement:

​

​	​	​	​	​	​	​
​	Year Ended		​	Year Ended		​
​	December 31,		​	December 31,		​
​	2024		​	2023		​
Contractual interest expense	$	—	​	$	30,198	​
Amortization of debt issuance costs	​	—	​	​	702	​
Total	$	—	​	$	30,900	​
Effective interest rate	​	—	%	​	13.1	%

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