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The Company (Details) $ in Thousands		1 Months Ended	12 Months Ended
	Jan. 11, 2025 USD ($)	Jan. 31, 2025 USD ($)	Dec. 31, 2024 USD ($) product	Dec. 31, 2023 USD ($)
Subsequent events
Number of products | product			2
Accumulated deficit			$ (3,646,873)	$ (3,283,578)
Subsequent Event | License and Collaboration Agreement | Novartis
Subsequent events
Cash proceeds from upfront payment on collaboration agreement	$ 1,000,000	$ 1,000,000

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