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Summary of significant accounting policies - Tangible Asset Impairment and Losses (Gains) on Transactions, Net (Details) $ in Thousands	12 Months Ended
	Dec. 31, 2024 USD ($)
Asset impairment and losses (gains) on transactions
Gain (loss) on sale of fixed assets	$ (4,298)
Tangible asset impairment	4,095
Gain on lease terminations	2,179
Gain on lease modifications	5,500
South Plainfield and Warren, New Jersey offices
Asset impairment and losses (gains) on transactions
Tangible asset impairment	4,100
Early-stage gene therapy program assets
Asset impairment and losses (gains) on transactions
Gain (loss) on sale of fixed assets	$ 4,400

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Amount of gain (loss) on modification of lease before expiration of lease term.

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- Definition

Amount of gain (loss) on sale or disposal of property, plant and equipment assets, including oil and gas property and timber property.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Section 45
-Paragraph 28
-Subparagraph (b)
-SubTopic 10
-Topic 230
-Publisher FASB
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Amount of gain (loss) on termination of lease before expiration of lease term.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 842
-SubTopic 20
-Name Accounting Standards Codification
-Section 40
-Paragraph 1
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479092/842-20-40-1

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The charge against earnings resulting from the aggregate write down of tangible assets from their carrying value to their fair value.

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-Topic 360
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
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-Publisher FASB
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