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Debt - (Tables)

3 Months Ended

Mar. 31, 2025

Debt Instrument, Redemption [Line Items]

Summary of liability for sale of future royalties

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​	​	​	​	​
​		Three Months Ended March 31,		​
Liability for sale of future royalties- (current and noncurrent)	​	2025		​
Beginning balance as of December 31, 2024	​	$	2,081,776	​
Less: Non-cash royalty revenue payable to Royalty Pharma	​	​	(32,974)	​
Plus: Non-cash interest expense recognized	​	​	49,661	​
Ending balance	​	$	2,098,463	​
Effective interest rate as of March 31, 2025	​		9.3%	​

2026 Convertible Notes

Debt Instrument, Redemption [Line Items]

Summary of convertible notes

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​	​	​	​	​	​	​	​
​		​	​	​	​	​	​
​	​	March 31, 2025		​	December 31, 2024		​
Principal	​	$	287,500	​	$	287,500	​
Less: Debt issuance costs	​		(1,788)	​		(2,088)	​
Net carrying amount	​	$	285,712	​	$	285,412	​

Summary of interest expense recognized related to the Convertible Notes

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​	​	​	​	​	​	​	​
​	​	​	Three Months Ended March 31,				​
​		2025		​	2024
Contractual interest expense	​	$	1,069	​	$	1,076	​
Amortization of debt issuance costs	​		299	​	​	296	​
Total	​	$	1,368	​	$	1,372	​
Effective interest rate	​		1.9	%	​	1.9	%

​

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