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Intangible assets and goodwill - (Tables)

3 Months Ended

Mar. 31, 2025

Goodwill and Intangible Assets Disclosure [Abstract]

Schedule of definite lived intangible assets

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Ending Balance at

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Foreign

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Ending Balance at

Definite-lived

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December 31,

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currency

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March 31,

intangibles assets, gross

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2024

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Additions

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translation

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2025

Waylivra

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​

12,397

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​

1,791

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​

495

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​

14,683

Tegsedi

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​

18,249

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​

878

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​

726

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​

19,853

Kebilidi

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​

10,731

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​

—

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​

—

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10,731

Upstaza

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​

106,937

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—

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—

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106,937

Total definite-lived intangibles, gross

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$

148,314

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$

2,669

​

$

1,221

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$

152,204

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Ending Balance at

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Foreign

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Ending Balance at

Definite-lived

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December 31,

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currency

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March 31,

intangibles assets, accumulated amortization

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2024

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Amortization

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translation

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2025

Waylivra

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(5,273)

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(540)

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(212)

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(6,025)

Tegsedi

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(5,609)

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(806)

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(226)

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(6,641)

Kebilidi

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(112)

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(224)

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—

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(336)

Upstaza

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(18,526)

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(2,228)

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—

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(20,754)

Total definite-lived intangibles, accumulated amortization

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$

(29,520)

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$

(3,798)

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$

(438)

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$

(33,756)

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Total definite-lived intangibles, net

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$

118,448

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Schedule of estimated future amortization of intangible assets

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​	​	​	​
​		As of March 31, 2025
2025	​	$	11,370
2026	​		15,162
2027	​		15,162
2028	​		15,162
2029 and thereafter	​		61,592
Total	​	$	118,448

X

- References

No definition available.

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X

- Definition

Tabular disclosure of assets, excluding financial assets and goodwill, lacking physical substance with a finite life, by either major class or business segment.

+ References

Reference 1: http://www.xbrl.org/2003/role/exampleRef
-Topic 350
-SubTopic 30
-Name Accounting Standards Codification
-Section 55
-Paragraph 40
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482640/350-30-55-40

Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 350
-SubTopic 30
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-Subparagraph (a)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482665/350-30-50-2

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- Definition

Tabular disclosure of the amount of amortization expense expected to be recorded in succeeding fiscal years for finite-lived intangible assets.

+ References

Reference 1: http://www.xbrl.org/2003/role/exampleRef
-Topic 350
-SubTopic 30
-Name Accounting Standards Codification
-Section 55
-Paragraph 40
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482640/350-30-55-40

Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 350
-SubTopic 30
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-Subparagraph (a)(3)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482665/350-30-50-2

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