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Fair value of financial instruments and marketable securities - Hierarchy (Details) - USD ($)	Mar. 31, 2025	Dec. 31, 2024
Financial assets and liabilities measured at fair value on recurring basis
Marketable securities - available for sale	$ 518,763,000	$ 330,953,000
Contingent consideration payable	0	800,000
Transfers of assets measured between Level 1, Level 2, and Level 3	0	0
Recurring basis
Financial assets and liabilities measured at fair value on recurring basis
Marketable securities - available for sale	518,763,000	330,953,000
Marketable securities - equity investments	28,187,000	29,034,000
ClearPoint Equity Investments	10,637,000	13,759,000
Recurring basis | Quoted prices in active markets for identical assets (Level 1)
Financial assets and liabilities measured at fair value on recurring basis
Marketable securities - equity investments	28,187,000	29,034,000
ClearPoint Equity Investments	10,637,000	13,759,000
Recurring basis | Significant other observable inputs (Level 2)
Financial assets and liabilities measured at fair value on recurring basis
Marketable securities - available for sale	$ 518,763,000	330,953,000
Recurring basis | Net Sales Milestones
Financial assets and liabilities measured at fair value on recurring basis
Contingent consideration payable		800,000
Recurring basis | Net Sales Milestones | Significant unobservable inputs (Level 3)
Financial assets and liabilities measured at fair value on recurring basis
Contingent consideration payable		$ 800,000

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