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Stock award plan - Narrative (Details) - USD ($) $ / shares in Units, $ in Thousands		1 Months Ended			3 Months Ended
	Jun. 08, 2022	Dec. 31, 2022	Jun. 30, 2021	Dec. 31, 2020	Mar. 31, 2025	Mar. 31, 2024	Apr. 30, 2022	May 31, 2021	Jan. 31, 2020
Stock option plan
Share-based compensation expense					$ 18,060	$ 18,378
Unrecognized compensation cost					$ 170,300
Weighted average remaining service period for recognition of unrecognized compensation cost					2 years 10 months 24 days
Stock option
Stock option plan
Granted (in shares)					802,745
Options forfeited (in shares)					320,327
Expected dividend yield (as a percent)					0.00%
Weighted average grant date fair value (in dollars per share)					$ 25.24
Restricted stock units
Stock option plan
Granted (in shares)					1,537,675
Employee Stock Purchase Plan
Stock option plan
Number of shares authorized (in shares)			2,000,000					1,000,000
Award requisite service period			6 months
Purchase price of common stock, percent			85.00%
Employee stock purchase plan, voting percentage limit			5.00%
Share-based compensation expense					$ 500
1998 Employee, Director, and Consultant Stock Option Plan, 2009 Equity and Long-term Incentive Plan, and 2013 Stock Incentive Plan | Common stock
Stock option plan
Number of shares available for issuance					0
Amended 2013 LTIP
Stock option plan
Number of shares available for issuance					4,984,677
Number of additional shares authorized (in shares)	8,475,000
Amended 2013 LTIP | Maximum
Stock option plan
Number of shares authorized (in shares)	16,724,212
2020 Inducement Stock Incentive Plan | Common stock
Stock option plan
Number of shares available for issuance					1,894,422
Number of additional shares authorized (in shares)		1,700,000		1,000,000
2020 Inducement Stock Incentive Plan | Common stock | Maximum
Stock option plan
Number of shares authorized (in shares)							1,300,000		1,000,000
2020 Inducement Stock Incentive Plan | Stock option
Stock option plan
Granted (in shares)					12,000
Stockholder's specified ownership percentage					10.00%
Vesting period					4 years
2020 Inducement Stock Incentive Plan | Stock option | Minimum
Stock option plan
Stock options granted, exercise price as percentage of the fair market value of common stock at grant date					100.00%
2020 Inducement Stock Incentive Plan | Stock option | Maximum
Stock option plan
Stock options granted to stockholder with specified ownership percentage, exercise price as percentage of the fair market value of common stock at grant date					110.00%
Expiration period					10 years
2020 Inducement Stock Incentive Plan | Restricted stock units
Stock option plan
Granted (in shares)					29,420

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