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Segment information - Significant Expenses by Segment (Details)
$ in Thousands
 3 Months Ended
Mar. 31, 2025
USD ($)
segment
Mar. 31, 2024
USD ($)
segment
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]    
Number of Operating Segments | segment 1 1
Total revenues $ 1,176,096 $ 210,118
Net income (loss) attributable to common stockholders 866,562 (91,576)
Income tax expense (63,266) (6,880)
Amortization 3,798 51,530
Operating segments | Life Science    
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]    
Total revenues 1,176,096 210,118
Cost of Product, Collaboration and License Sales 7,707 5,195
Program Spend 48,158 48,364
Employee Costs 67,699 63,997
Manufacturing Costs 14,950 18,081
Administrative Costs 18,414 16,872
Occupancy Costs 7,183 9,893
Other segment items 145,423 139,292
Net income (loss) attributable to common stockholders 866,562 (91,576)
Interest income (17,245) (10,940)
Interest expense 51,337 51,774
Income tax expense 63,266 6,880
Depreciation 3,458 3,867
Amortization 3,798 51,530
All other 40,809 36,181
Other segment items $ 145,423 $ 139,292