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Summary of significant accounting policies - Tangible asset impairment and losses (gains) on transactions, net (Details) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2025 | Jun. 30, 2024 | Jun. 30, 2025 | Jun. 30, 2024
Asset impairment and losses (gains) on transactions |  |  |  |
Gain (loss) on sale of fixed assets |  |  | $ (77) | $ (3,772)
Tangible asset impairment | $ 100 |  | $ 99 | 168
Gain on lease terminations |  | $ 2,200 |  | 2,179
Gain on lease modifications |  | 400 |  | 400
Early-stage gene therapy program assets |  |  |  |
Asset impairment and losses (gains) on transactions |  |  |  |
Gain (loss) on sale of fixed assets |  | (4,200) |  | (4,200)
Tangible asset impairment |  | $ 200 |  | $ 200

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- Definition Amount of gain (loss) on sale or disposal of property, plant and equipment assets, including oil and gas property and timber property. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 45 -Paragraph 28 -Subparagraph (b) -SubTopic 10 -Topic 230 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482740/230-10-45-28 + Details
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- Definition Amount of gain (loss) on termination of lease before expiration of lease term. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 842 -SubTopic 20 -Name Accounting Standards Codification -Section 40 -Paragraph 1 -Publisher FASB -URI https://asc.fasb.org/1943274/2147479092/842-20-40-1 + Details
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