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Accounts payable and accrued expenses | 6 Months Ended
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Jun. 30, 2025
Payables and Accruals [Abstract] |
Accounts payable and accrued expenses | 5. Accounts payable and accrued expenses Accounts payable and accrued expenses at June 30, 2025 and December 31, 2024 consist of the following: ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | June 30, | ​ | December 31, | ​
​ |  | 2025 |  | 2024 | ​
Employee compensation, benefits, and related accruals | ​ | $ | 38,246 | ​ | $ | 61,575 | ​
Income tax payable | ​ | ​ | 39,923 | ​ | ​ | 4,701 | ​
Consulting and contracted research | ​ |  | 20,671 | ​ |  | 19,909 | ​
Sales allowance | ​ |  | 58,783 | ​ |  | 58,644 | ​
Sales rebates | ​ |  | 95,871 | ​ |  | 101,613 | ​
Royalties | ​ | ​ | 5,493 | ​ | ​ | 8,953 | ​
Accounts payable | ​ |  | 26,505 | ​ |  | 17,274 | ​
Milestone payable | ​ | ​ | 25,150 | ​ | ​ | 11,025 | ​
Other | ​ |  | 28,303 | ​ |  | 20,598 | ​
Total | ​ | $ | 338,945 | ​ | $ | 304,292 | ​
​ As of June 30, 2025, the Company does no t have any accrued restructuring costs included above within employee compensation, benefits, and related accruals. As of December 31, 2024, there were $0.1 million of accrued restructuring costs included above within employee compensation, benefits, and related accruals from a reduction in workforce in the year ended December 31, 2023 in connection with the Company’s strategic pipeline prioritization and discontinuation of its preclinical and early research programs in its gene therapy platform.

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- Definition The entire disclosure for accounts payable, accrued expenses, and other liabilities that are classified as current at the end of the reporting period. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 720 -SubTopic 30 -Name Accounting Standards Codification -Section 45 -Paragraph 1 -Publisher FASB -URI https://asc.fasb.org/1943274/2147483384/720-30-45-1 + Details
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