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Revenue recognition (Tables)

6 Months Ended

Jun. 30, 2025

Revenue from Contract with Customer [Abstract]

Schedule of disaggregation of net product revenue


		Three Months Ended June 30,
			2025								2024
			United States			International			Total			United States			International			Total
Translarna		$	—		$	59,470		$	59,470		$	—		$	70,350		$	70,350
Emflaza			36,353			—			36,353			47,296			—			47,296
Upstaza/Kebilidi			—			11,889			11,889			—			1,589			1,589
All other products			—			10,617			10,617			—			13,985			13,985
Total net product revenue		$	36,353		$	81,976		$	118,329		$	47,296		$	85,924		$	133,220


		Six Months Ended June 30,
		2025									2024
			United States			International			Total			United States			International			Total
Translarna		$	—		$	145,624		$	145,624		$	—		$	173,934		$	173,934
Emflaza			84,142			—			84,142			104,777			—			104,777
All other products			—			41,989			41,989			—			32,113			32,113
Total net product revenue		$	84,142		$	187,613		$	271,755		$	104,777		$	206,047		$	310,824


		Three Months Ended June 30,						Six Months Ended June 30,
		2025			2024			2025			2024
United States		$	36,353		$	47,296		$	84,142		$	104,777
Russia			18,124			2,146			56,638			54,751
Brazil			40,951			30,375			50,456			39,085
All other countries			22,901			53,403			80,519			112,211
Total net product revenue		$	118,329		$	133,220		$	271,755		$	310,824