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Segment information (Tables)

6 Months Ended

Jun. 30, 2025

Segment Reporting [Abstract]

Schedule of significant expense categories by operating segment


			Three months ended June 30,						Six months ended June 30,
		2025			2024			2025			2024
Total revenues		$	178,875		$	186,704		$	1,354,971		$	396,822
Less:
Cost of product, collaboration and license sales			8,093			4,477			15,800			9,671
Program spend			49,705			52,959			97,863			101,323
Employee costs			65,593			59,558			133,292			123,555
Manufacturing costs			19,519			12,325			34,470			30,406
Administrative costs			17,896			18,623			36,310			35,495
Occupancy costs			6,643			9,588			13,825			19,481
Milestones			—			15,000			—			15,000
Other segment items (a)			76,275			113,353			221,698			252,646
Segment net (loss) income		$	(64,849)		$	(99,179)		$	801,713		$	(190,755)
Reconciliation of profit or loss
Adjustments and reconciling items			—			—			—			—
Consolidated net (loss) income		$	(64,849)		$	(99,179)		$	801,713		$	(190,755)

(a)	Other segment items includes the following:


			Three months ended June 30,						Six months ended June 30,
			2025			2024			2025			2024
Interest income		$	(20,991)		$	(10,494)		$	(38,236)		$	(21,434)
Interest expense			51,349			53,984			102,686			105,758
Income tax (benefit) expense			(6,203)			13,446			57,063			20,326
Depreciation			3,573			4,155			7,031			8,021
Amortization			4,061			2,865			7,859			54,395
All other (b)			44,486			49,397			85,295			85,580
Total other segment items		$	76,275		$	113,353		$	221,698		$	252,646

(b)	All other includes cost of goods sold, royalty, travel and expense, distribution costs, bad debt expense, finance costs, contract labor costs, stock compensation expense, change in the fair value of contingent consideration, and other expense.

Schedule of other segment items

(a)	Other segment items includes the following:


			Three months ended June 30,						Six months ended June 30,
			2025			2024			2025			2024
Interest income		$	(20,991)		$	(10,494)		$	(38,236)		$	(21,434)
Interest expense			51,349			53,984			102,686			105,758
Income tax (benefit) expense			(6,203)			13,446			57,063			20,326
Depreciation			3,573			4,155			7,031			8,021
Amortization			4,061			2,865			7,859			54,395
All other (b)			44,486			49,397			85,295			85,580
Total other segment items		$	76,275		$	113,353		$	221,698		$	252,646

(b)	All other includes cost of goods sold, royalty, travel and expense, distribution costs, bad debt expense, finance costs, contract labor costs, stock compensation expense, change in the fair value of contingent consideration, and other expense.