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Summary of significant accounting policies - Tangible asset impairment and losses (gains) on transactions, net (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2025	Jun. 30, 2024	Jun. 30, 2025	Jun. 30, 2024
Asset impairment and losses (gains) on transactions
Gain (loss) on sale of fixed assets			$ (77)	$ (3,772)
Tangible asset impairment	$ 100		$ 99	168
Gain on lease terminations		$ 2,200		2,179
Gain on lease modifications		400		400
Early-stage gene therapy program assets
Asset impairment and losses (gains) on transactions
Gain (loss) on sale of fixed assets		(4,200)		(4,200)
Tangible asset impairment		$ 200		$ 200

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- Definition

Amount of gain (loss) on sale or disposal of property, plant and equipment assets, including oil and gas property and timber property.

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Amount of gain (loss) on termination of lease before expiration of lease term.

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The charge against earnings resulting from the aggregate write down of tangible assets from their carrying value to their fair value.

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