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Revenue recognition - Disaggregated Net Product Revenue by Country (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2025	Jun. 30, 2024	Jun. 30, 2025	Jun. 30, 2024
Disaggregation of Revenue [Line Items]
Total revenues	$ 178,875	$ 186,704	$ 1,354,971	$ 396,822
Product
Disaggregation of Revenue [Line Items]
Total revenues	118,329	133,220	271,755	310,824
United States
Disaggregation of Revenue [Line Items]
Total revenues	36,353	47,296	84,142	104,777
United States | Product
Disaggregation of Revenue [Line Items]
Total revenues	36,353	47,296	84,142	104,777
Russia
Disaggregation of Revenue [Line Items]
Total revenues	18,124	2,146	56,638	54,751
Brazil
Disaggregation of Revenue [Line Items]
Total revenues	40,951	30,375	50,456	39,085
All other countries
Disaggregation of Revenue [Line Items]
Total revenues	$ 22,901	$ 53,403	$ 80,519	$ 112,211

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