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Fair value of financial instruments and marketable securities - (Tables) | 9 Months Ended
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Sep. 30, 2025
Fair value of financial instruments and marketable securities |
Schedule of marketable securities | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Ending | ​ | ​ | ​ | ​ | Foreign | ​ | ​ | ​ | ​ | ​ | ​ | ​ | Ending
​ | ​ | Balance at | ​ | ​ | ​ | ​ | Currency | ​ | ​ | ​ | ​ | ​ | ​ | ​ | Balance at
​ | ​ | June 30, | ​ | Unrealized | ​ | Unrealized | ​ | Investments | ​ | Redemptions/ | ​ | September 30,
​ |  | 2025 |  | Gain |  | Gain |  | Purchased |  | Sale |  | 2025
Marketable securities - equity investments | ​ | $ | 34,203 | ​ | ​ | 1,622 | ​ | ​ | 1,605 | ​ | ​ | 29,508 | ​ | ​ | (22,982) | ​ | ​ | 43,956
ClearPoint Equity Investments | ​ | ​ | 10,681 | ​ | ​ | 8,812 | ​ | ​ | — | ​ | ​ | — | ​ | ​ | — | ​ | ​ | 19,493
Total Fair Value | ​ | $ | 44,884 | ​ | $ | 10,434 | ​ | $ | 1,605 | ​ | $ | 29,508 | ​ | $ | (22,982) | ​ | $ | 63,449
​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Ending | ​ | ​ | ​ | ​ | ​ | ​ | Foreign | ​ | ​ | ​ | ​ | ​ | ​ | Ending
​ | ​ | Balance at | ​ | ​ | ​ | ​ | ​ | ​ | Currency | ​ | ​ | ​ | ​ | ​ | ​ | Balance at
​ | ​ | June 30, | ​ | Unrealized | ​ | Realized | ​ | Unrealized | ​ | Investments | ​ | Redemptions/ | ​ | September 30,
​ |  | 2024 |  | Gain | ​ | Loss |  | Gain |  | Purchased |  | Sale | ​ | 2024
Marketable securities - equity investments | ​ | $ | 16,889 | ​ | ​ | 812 | ​ | ​ | — | ​ | ​ | 400 | ​ | ​ | 32,208 | ​ | ​ | (21,051) | ​ | $ | 29,258
ClearPoint Equity Investments | ​ | ​ | 4,822 | ​ | ​ | 5,206 | ​ | ​ | — | ​ | ​ | — | ​ | ​ | — | ​ | ​ | — | ​ | ​ | 10,028
ClearPoint convertible debt security | ​ | ​ | 10,622 | ​ | ​ | — | ​ | ​ | (622) | ​ | ​ | — | ​ | ​ | — | ​ | ​ | (10,000) | ​ | ​ | —
Total Fair Value | ​ | $ | 32,333 | ​ | $ | 6,018 | ​ | $ | (622) | ​ | $ | 400 | ​ | $ | 32,208 | ​ | $ | (31,051) | ​ | $ | 39,286
​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Ending | ​ | ​ | ​ | ​ | Foreign | ​ | ​ | ​ | ​ | ​ | ​ | ​ | Ending | ​
​ | ​ | Balance at | ​ | ​ | ​ | ​ | Currency | ​ | ​ | ​ | ​ | ​ | ​ | ​ | Balance at | ​
​ | ​ | December 31, | ​ | Unrealized | ​ | Unrealized | ​ | Investments | ​ | Redemptions/ | ​ | September 30, | ​
​ |  | 2024 |  | Gain |  | Gain |  | Purchased |  | Sale |  | 2025 | ​
Marketable securities - equity investments | ​ | $ | 29,034 | ​ | ​ | 3,160 | ​ | ​ | 5,337 | ​ | ​ | 46,537 | ​ | ​ | (40,112) | ​ | ​ | 43,956 | ​
ClearPoint Equity Investments | ​ | ​ | 13,759 | ​ | ​ | 5,734 | ​ | ​ | — | ​ | ​ | — | ​ | ​ | — | ​ | ​ | 19,493 | ​
Total Fair Value | ​ | $ | 42,793 | ​ | $ | 8,894 | ​ | $ | 5,337 | ​ | $ | 46,537 | ​ | $ | (40,112) | ​ | $ | 63,449 | ​
​ ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Ending | ​ | ​ | ​ | ​ | ​ | ​ | Foreign | ​ | ​ | ​ | ​ | ​ | ​ | Ending
​ | ​ | Balance at | ​ | ​ | ​ | ​ | ​ | ​ | Currency | ​ | ​ | ​ | ​ | ​ | ​ | Balance at
​ | ​ | December 31, | ​ | Unrealized | ​ | Realized | ​ | Unrealized | ​ | Investments | ​ | Redemptions/ | ​ | September 30,
​ |  | 2023 |  | Gain/(Loss) |  | Loss |  | Loss |  | Purchased |  | Sale |  | 2024
Marketable securities - equity investments | ​ | $ | 22,634 | ​ | ​ | 1,923 | ​ | ​ | — | ​ | ​ | (3,289) | ​ | ​ | 49,614 | ​ | ​ | (41,624) | ​ | $ | 29,258
ClearPoint Equity Investments | ​ | ​ | 6,074 | ​ | ​ | 3,954 | ​ | ​ | — | ​ | ​ | — | ​ | ​ | — | ​ | ​ | — | ​ | ​ | 10,028
ClearPoint convertible debt security | ​ | ​ | 12,553 | ​ | ​ | (1,931) | ​ | ​ | (622) | ​ | ​ | — | ​ | ​ | — | ​ | ​ | (10,000) | ​ | ​ | —
Total Fair Value | ​ | $ | 41,261 | ​ | $ | 3,946 | ​ | $ | (622) | ​ | $ | (3,289) | ​ | $ | 49,614 | ​ | $ | (51,624) | ​ | $ | 39,286
Schedule of financial assets and liabilities that are required to be measured at fair value on a recurring basis | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | September 30, 2025
​ |  | ​ | ​ |  | Quoted prices |  | Significant |  | ​ | ​
​ | ​ | ​ | ​ |  | in active |  | other |  | Significant
​ | ​ | ​ | ​ |  | markets for |  | observable |  | unobservable
​ | ​ | ​ | ​ |  | identical assets |  | inputs |  | inputs
​ |  | Total |  | (level 1) |  | (level 2) |  | (level 3)
Marketable securities - available for sale | ​ | $ | 971,244 | ​ | $ | — | ​ | $ | 971,244 | ​ | $ | —
Marketable securities - equity investments | ​ | $ | 43,956 | ​ | $ | 43,956 | ​ | $ | — | ​ | $ | —
ClearPoint Equity Investments | ​ | $ | 19,493 | ​ | $ | 19,493 | ​ | $ | — | ​ | $ | —
​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | December 31, 2024
​ |  | ​ | ​ |  | Quoted prices |  | Significant |  | ​ | ​
​ | ​ | ​ | ​ |  | in active |  | other |  | Significant
​ | ​ | ​ | ​ |  | markets for |  | observable |  | unobservable
​ | ​ | ​ | ​ |  | identical assets |  | inputs |  | inputs
​ |  | Total |  | (level 1) |  | (level 2) |  | (level 3)
Marketable securities - available for sale | ​ | $ | 330,953 | ​ | $ | — | ​ | $ | 330,953 | ​ | $ | —
Marketable securities - equity investments | ​ | $ | 29,034 | ​ | $ | 29,034 | ​ | $ | — | ​ | $ | —
ClearPoint Equity Investments | ​ | $ | 13,759 | ​ | $ | 13,759 | ​ | $ | — | ​ | $ | —
Contingent consideration payable- net sales milestones | ​ | $ | 800 | ​ | $ | — | ​ | $ | — | ​ | $ | 800
​
Summary of marketable securities accounted for as available-for-sale debt securities | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | September 30, 2025
​ |  | Amortized |  | Gross Unrealized | ​ | ​ | ​
​ |  | Cost |  | Gains |  | Losses |  | Fair Value
Commercial paper | ​ | $ | 106,556 | ​ | $ | 8 | ​ | $ | (3) | ​ | $ | 106,561
Corporate debt securities | ​ | ​ | 243,257 | ​ | ​ | 160 | ​ | ​ | (2) | ​ | ​ | 243,415
Government obligations | ​ | ​ | 620,760 | ​ | ​ | 518 | ​ | ​ | (10) | ​ | ​ | 621,268
Total | ​ | $ | 970,573 | ​ | $ | 686 | ​ | $ | (15) | ​ | $ | 971,244
​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | December 31, 2024
​ |  | Amortized |  | Gross Unrealized | ​ | ​ | ​
​ |  | Cost |  | Gains |  | Losses |  | Fair Value
Commercial paper | ​ | $ | 44,780 | ​ | $ | — | ​ | $ | (1) | ​ | $ | 44,779
Corporate debt securities | ​ |  | 89,320 | ​ | ​ | 76 | ​ | ​ | (75) | ​ | ​ | 89,321
Government obligations | ​ | ​ | 196,584 | ​ | ​ | 269 | ​ | ​ | — | ​ | ​ | 196,853
Total | ​ | $ | 330,684 | ​ | $ | 345 | ​ | $ | (76) | ​ | $ | 330,953
​
Summary of unrealized losses and fair values of available-for-sale debt securities in a continuous unrealized loss position | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | September 30, 2025
​ |  | Securities in an unrealized loss |  | Securities in an unrealized loss |  | ​ | ​ | ​ | ​ | ​
​ |  | position less than 12 months |  | position greater than or equal to 12 months | ​ | Total
​ |  | Unrealized losses |  | Fair Value |  | Unrealized losses |  | Fair Value |  | Unrealized losses |  | Fair Value
Commercial paper | ​ | $ | (3) | ​ | ​ | 59,850 | ​ | ​ | — | ​ | ​ | — | ​ | ​ | (3) | ​ | $ | 59,850
Corporate debt securities | ​ | $ | (2) | ​ | ​ | 44,500 | ​ | ​ | — | ​ | ​ | — | ​ | ​ | (2) | ​ | $ | 44,500
Government obligations | ​ | $ | (10) | ​ | ​ | 30,001 | ​ | ​ | — | ​ | ​ | — | ​ | ​ | (10) | ​ | $ | 30,001
Total | ​ | $ | (15) | ​ | $ | 134,351 | ​ | $ | — | ​ | $ | — | ​ | $ | (15) | ​ | $ | 134,351
​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | December 31, 2024
​ |  | Securities in an unrealized loss |  | Securities in an unrealized loss |  | ​ | ​ | ​ | ​ | ​
​ |  | position less than 12 months |  | position greater than or equal to 12 months | ​ | Total
​ |  | Unrealized losses |  | Fair Value |  | Unrealized losses |  | Fair Value |  | Unrealized losses |  | Fair Value
Commercial paper | ​ | $ | (1) | ​ | ​ | 29,810 | ​ | ​ | — | ​ | ​ | — | ​ | ​ | (1) | ​ | $ | 29,810
Corporate debt securities | ​ | $ | (75) | ​ | ​ | 59,550 | ​ | ​ | — | ​ | ​ | — | ​ | ​ | (75) | ​ | $ | 59,550
Total | ​ | $ | (76) | ​ | $ | 89,360 | ​ | $ | — | ​ | $ | — | ​ | $ | (76) | ​ | $ | 89,360
Schedule of available-for-sale debt securities | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | September 30, 2025
​ |  | Less Than |  | More Than
​ |  | 12 Months |  | 12 Months
Commercial paper | ​ | $ | 106,561 | ​ | $ | —
Corporate debt securities | ​ | ​ | 243,415 | ​ | ​ | —
Government obligations | ​ | ​ | 621,268 | ​ | ​ | —
Total | ​ | $ | 971,244 | ​ | $ | —
​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | December 31, 2024
​ |  | Less Than |  | More Than
​ |  | 12 Months |  | 12 Months
Commercial paper | ​ | $ | 44,779 | ​ | $ | —
Corporate debt securities | ​ |  | 89,321 | ​ |  | —
Government obligations | ​ | ​ | 196,853 | ​ | ​ | —
Total | ​ | $ | 330,953 | ​ | $ | —
​

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- Definition Tabular disclosure of assets and liabilities, including [financial] instruments measured at fair value that are classified in stockholders' equity, if any, that are measured at fair value on a recurring basis. The disclosures contemplated herein include the fair value measurements at the reporting date by the level within the fair value hierarchy in which the fair value measurements in their entirety fall, segregating fair value measurements using quoted prices in active markets for identical assets (Level 1), significant other observable inputs (Level 2), and significant unobservable inputs (Level 3). + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 820 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482106/820-10-50-2 Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 820 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482106/820-10-50-2 + Details
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