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Stock award plan - (Tables) | 9 Months Ended
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Sep. 30, 2025
Stock award plan |
Summary of stock option activity | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | ​ |  | ​ | ​ |  | Weighted- |  |  | ​ | ​
​ | ​ | ​ | ​ | Weighted- | ​ | average | ​ | ​ | Aggregate
​ | ​ | ​ | ​ | average | ​ | remaining | ​ | ​ | intrinsic
​ | ​ | Number of | ​ | exercise | ​ | contractual | ​ | ​ | value(in
​ | ​ | options | ​ | price | ​ | term | ​ | ​ | thousands)
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ |  | ​ | ​ | ​
Outstanding at December 31, 2024 |  | 8,482,489 | ​ | $ | 42.29 |  |  |  | ​ | ​ |
Granted |  | 841,945 | ​ | $ | 47.12 |  |  |  | ​ | ​ |
Exercised |  | (953,414) | ​ | $ | 35.75 |  |  |  | ​ | ​ |
Forfeited/Cancelled |  | (564,709) | ​ | $ | 53.91 |  |  |  | ​ | ​ |
Outstanding at September 30, 2025 |  | 7,806,311 | ​ | $ | 42.77 |  | 5.66 | years | ​ | $ | 151,190
Expected to vest at September 30, 2025 |  | 1,524,459 | ​ | $ | 39.30 |  | 8.53 | years | ​ | $ | 33,651
Exercisable at September 30, 2025 |  | 6,126,727 | ​ | $ | 43.71 |  | 4.86 | years | ​ | $ | 114,211
​
Schedule of assumptions used to estimate fair values of grants made on the date of grant | ​
​ | ​ | ​ | ​
​ |  | Nine months ended |
​ |  | September 30, 2025 |
Risk-free interest rate |  | 3.81% - 4.44% |
Expected volatility |  | 55% - 56% |
Expected term |  | 5.5 years |
Summary of information on the Company's restricted stock | ​
​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Restricted Stock Units
​ | ​ | ​ | ​ | Weighted
​ | ​ | ​ | ​ | Average
​ | ​ | ​ | ​ | Grant
​ | ​ | Number of | ​ | Date
​ |  | Shares |  | Fair Value
Unvested at December 31, 2024 | ​ | 3,527,575 | ​ | $ | 33.39
Granted |  | 1,615,305 | ​ | ​ | 47.16
PSUs with conditions satisfied |  | 75,000 | ​ | ​ | 28.58
Vested | ​ | (1,201,681) | ​ | ​ | 36.79
Forfeited |  | (227,396) | ​ | ​ | 35.27
Unvested at September 30, 2025 |  | 3,788,803 | ​ | $ | 37.98
Schedule of information about Performance-based restricted stock units | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Performance-based Restricted Stock Units
​ |  | Performance based |  | Market Conditions | ​ | Total
Total PSUs granted for which the performance or market conditions were not yet satisfied at December 31, 2024 | ​ | 175,000 | ​ | 31,250 | ​ | 206,250
PSUs with performance or market conditions satisfied during the period |  | (75,000) | ​ | — | ​ | (75,000)
Total PSUs granted for which the performance or market conditions were not yet satisfied at September 30, 2025 |  | 100,000 | ​ | 31,250 | ​ | 131,250
Schedule of share-based compensation expense recorded in the statement of operations | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Three Months Ended September 30, | ​ | Nine Months Ended September 30,
​ |  | 2025 |  | 2024 |  | 2025 |  | 2024
Research and development | ​ | $ | 9,133 | ​ | $ | 9,416 | ​ | $ | 26,827 | ​ | $ | 27,810
Selling, general and administrative | ​ |  | 10,293 | ​ |  | 10,339 | ​ |  | 29,202 | ​ |  | 29,566
Total | ​ | $ | 19,426 | ​ | $ | 19,755 | ​ | $ | 56,029 | ​ | $ | 57,376
​

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