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Revenue recognition (Tables)

9 Months Ended

Sep. 30, 2025

Revenue from Contract with Customer [Abstract]

Schedule of disaggregation of net product revenue


		Three Months Ended September 30,
			2025								2024
			United States			International			Total			United States			International			Total
Translarna		$	—		$	50,665		$	50,665		$	—		$	72,283		$	72,283
Emflaza			35,160			—			35,160			51,941			—			51,941
Sephience			14,365			5,198			19,563			—			—			—
Upstaza/Kebilidi			6,898			8,837			15,735			—			—			—
All other products			—			9,833			9,833			—			11,197			11,197
Total net product revenue		$	56,423		$	74,533		$	130,956		$	51,941		$	83,480		$	135,421


		Nine Months Ended September 30,
		2025									2024
			United States			International			Total			United States			International			Total
Translarna		$	—		$	196,289		$	196,289		$	—		$	246,217		$	246,217
Emflaza			119,303			—			119,303			156,718			—			156,718
Sephience			14,365			5,198			19,563			—			—			—
Upstaza/Kebilidi			6,898			29,385			36,283			—			9,648			9,648
All other products			—			31,273			31,273			—			33,662			33,662
Total net product revenue		$	140,566		$	262,145		$	402,711		$	156,718		$	289,527		$	446,245


		Three Months Ended September 30,						Nine Months Ended September 30,
		2025			2024			2025			2024
United States		$	56,423		$	51,941		$	140,566		$	156,718
Russia			25,107			965			81,745			55,716
Brazil			9,222			29,219			59,678			68,304
All other countries			40,204			53,296			120,722			165,507
Total net product revenue		$	130,956		$	135,421		$	402,711		$	446,245