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Summary of significant accounting policies - Tangible asset impairment and losses (gains) on transactions, net (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025	Sep. 30, 2024
Asset impairment and losses (gains) on transactions
Gain (loss) on sale of fixed assets	$ (100)		$ (130)	$ (4,298)
Tangible asset impairment	$ 400		$ 518	1,486
Gain on lease terminations				2,179
South Plainfield, New Jersey office
Asset impairment and losses (gains) on transactions
Tangible asset impairment		$ 1,300		1,500
Early-stage gene therapy program assets
Asset impairment and losses (gains) on transactions
Gain (loss) on sale of fixed assets				4,400
Other fixed assets
Asset impairment and losses (gains) on transactions
Gain (loss) on sale of fixed assets		$ 500		$ 100

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Amount of gain (loss) on sale or disposal of property, plant and equipment assets, including oil and gas property and timber property.

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Amount of gain (loss) on termination of lease before expiration of lease term.

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