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Revenue recognition - Disaggregated Net Product Revenue by Country (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025	Sep. 30, 2024
Disaggregation of Revenue [Line Items]
Total revenues	$ 211,007	$ 196,786	$ 1,565,978	$ 593,608
Product
Disaggregation of Revenue [Line Items]
Total revenues	130,956	135,421	402,711	446,245
United States
Disaggregation of Revenue [Line Items]
Total revenues	56,423	51,941	140,566	156,718
United States | Product
Disaggregation of Revenue [Line Items]
Total revenues	56,423	51,941	140,566	156,718
Russia
Disaggregation of Revenue [Line Items]
Total revenues	25,107	965	81,745	55,716
Brazil
Disaggregation of Revenue [Line Items]
Total revenues	9,222	29,219	59,678	68,304
All other countries
Disaggregation of Revenue [Line Items]
Total revenues	$ 40,204	$ 53,296	$ 120,722	$ 165,507

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