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Share-based Compensation - Schedule of Share-based Compensation Expense (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2021	Jun. 30, 2020	Jun. 30, 2021	Jun. 30, 2020
Share-based compensation Expense
Total share-based compensation expense	$ 27,552	$ 22,846	$ 43,003	$ 42,659
Cost of goods manufactured and sold
Share-based compensation Expense
Total share-based compensation expense	2,683	2,015	4,861	3,980
Research and development
Share-based compensation Expense
Total share-based compensation expense	7,131	6,478	11,194	12,638
Selling, general and administrative
Share-based compensation Expense
Total share-based compensation expense	$ 17,738	$ 14,353	$ 26,948	$ 26,041

X

- Definition

Amount of expense for award under share-based payment arrangement. Excludes amount capitalized.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 1
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-URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5047-113901

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-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section S99
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-URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901

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+ References

No definition available.

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