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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (unaudited) - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2021
Jun. 30, 2020
CASH FLOWS FROM OPERATING ACTIVITIES:    
Net loss $ (20,054) $ (68,085)
Adjustments to reconcile net loss to cash flows from operating activities:    
Depreciation and amortization 38,119 40,946
Share-based compensation expense 43,003 42,659
Deferred income taxes 10,806 7,665
Change in the fair value of contingent consideration (4,518) (12,700)
Loss on debt extinguishment 171  
Other non-cash charges 1,302 690
Changes in assets and liabilities:    
Receivables (22,194) 19,731
Contract assets 5,607 (854)
Inventory (11,232) (13,782)
Prepaid expenses and other assets 2,029 7,645
Right-of-use assets 8,595 8,594
Accounts payable and accrued expenses (52,629) (68,260)
Contract liabilities (3,108) (2,364)
Operating lease liabilities (7,821) (6,940)
Other long-term liabilities (159) 351
Cash flows used in operating activities (12,083) (44,704)
CASH FLOWS FROM INVESTING ACTIVITIES:    
Additions of property, plant and equipment (14,546) (30,372)
Proceeds from the sale of equipment 177 5
Proceeds from contingent consideration 7,889  
Payment made for licensed IP (1,000)  
Purchases of investments (201,774) (85,649)
Sales and maturities of investments 175,499 147,859
Cash flows (used in) provided by investing activities (33,755) 31,843
CASH FLOWS FROM FINANCING ACTIVITIES:    
Proceeds from the issuance of ordinary shares under share-based compensation arrangements 20,498 6,919
Employee taxes paid related to net share settlement of equity awards (11,120) (7,406)
Proceeds from the issuance of long-term debt 23,567  
Payment made for debt extinguishment (977)  
Principal payments of long-term debt (750) (1,421)
Cash flows provided by (used in) financing activities 31,218 (1,908)
NET DECREASE IN CASH AND CASH EQUIVALENTS (14,620) (14,769)
CASH AND CASH EQUIVALENTS—Beginning of period 272,961 203,771
CASH AND CASH EQUIVALENTS—End of period 258,341 189,002
Non-cash investing and financing activities:    
Purchased capital expenditures included in accounts payable and accrued expenses $ 1,023 $ 4,431