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Investments - Schedule of Investments (Details) - USD ($) $ in Thousands | Sep. 30, 2022 | Dec. 31, 2021
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Available-for-sale securities: |  |
Short-term investments, Amortized Cost | $ 320,732 | $ 198,596
Short-term investments, Gross Unrealized Gains | 4 | 287
Short-term investments, Gross Unrealized Losses, Less than One Year | (2,994) | (116)
Short-term investments, Gross Unrealized Losses, Greater than One Year | (1,517) |
Short-term investments, Estimated Fair Value | 316,225 | 198,767
Long-term investments, Amortized Cost | 172,168 | 228,991
Long-term investments, Gross Unrealized Losses, Less than One Year | (4,525) | (1,381)
Long-term investments, Gross Unrealized Losses, Greater than One Year | (2,535) |
Long-term investments, Estimated Fair Value | 165,108 | 227,610
Held-to-maturity securities: |  |
Estimated Fair Value | 1,820 |
Long-term Investments |  |
Amortized Cost | 173,988 | 230,811
Gross Unrealized Losses, Less than One Year | (4,525) | (1,381)
Gross Unrealized Losses, Greater than One Year | (2,535) |
Total long-term investments | 166,928 | 229,430
Total investments |  |
Amortized Cost | 494,720 | 429,407
Gross Unrealized Gains | 4 | 287
Gross Unrealized Losses, Less than One Year | (7,519) | (1,497)
Gross Unrealized Losses, Greater than One Year | (4,052) |
Estimated Fair Value | 483,153 | 428,197
Certificates of deposit |  |
Held-to-maturity securities: |  |
Amortized Cost | 1,820 | 1,820
Estimated Fair Value | 1,820 | 1,820
Corporate debt securities |  |
Available-for-sale securities: |  |
Short-term investments, Amortized Cost | 135,140 | 85,201
Short-term investments, Gross Unrealized Gains |  | 177
Short-term investments, Gross Unrealized Losses, Less than One Year | (1,860) | (39)
Short-term investments, Gross Unrealized Losses, Greater than One Year | (712) |
Short-term investments, Estimated Fair Value | 132,568 | 85,339
Long-term investments, Amortized Cost | 87,038 | 111,793
Long-term investments, Gross Unrealized Losses, Less than One Year | (2,757) | (654)
Long-term investments, Gross Unrealized Losses, Greater than One Year | (606) |
Long-term investments, Estimated Fair Value | 83,675 | 111,139
U.S. government and agency debt securities |  |
Available-for-sale securities: |  |
Short-term investments, Amortized Cost | 135,444 | 45,349
Short-term investments, Gross Unrealized Gains | 4 | 35
Short-term investments, Gross Unrealized Losses, Less than One Year | (823) | (24)
Short-term investments, Gross Unrealized Losses, Greater than One Year | (569) |
Short-term investments, Estimated Fair Value | 134,056 | 45,360
Long-term investments, Amortized Cost | 73,109 | 81,296
Long-term investments, Gross Unrealized Losses, Less than One Year | (1,768) | (517)
Long-term investments, Gross Unrealized Losses, Greater than One Year | (1,374) |
Long-term investments, Estimated Fair Value | 69,967 | 80,779
Non-U.S. government debt securities |  |
Available-for-sale securities: |  |
Short-term investments, Amortized Cost | 50,148 | 68,046
Short-term investments, Gross Unrealized Gains |  | 75
Short-term investments, Gross Unrealized Losses, Less than One Year | (311) | (53)
Short-term investments, Gross Unrealized Losses, Greater than One Year | (236) |
Short-term investments, Estimated Fair Value | 49,601 | 68,068
Long-term investments, Amortized Cost | 12,021 | 35,902
Long-term investments, Gross Unrealized Losses, Less than One Year |  | (210)
Long-term investments, Gross Unrealized Losses, Greater than One Year | (555) |
Long-term investments, Estimated Fair Value | $ 11,466 | $ 35,692

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