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Revenue from Contracts with Customers - Additional Information (Details) - USD ($) $ in Thousands		1 Months Ended	3 Months Ended				9 Months Ended
	Oct. 13, 2022	Oct. 31, 2022	Dec. 31, 2022	Sep. 30, 2022	Jun. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021	Dec. 31, 2021
Disaggregation Of Revenue [Line Items]
Contract assets				$ 10,105			$ 10,105		$ 13,363
Contract liabilities				8,639			8,639		17,830
Royalty revenue				252,357		$ 294,141	807,121	$ 849,288
Contract liabilities–short-term
Disaggregation Of Revenue [Line Items]
Contract liabilities				4,000			4,000		6,300
Other long-term liabilities
Disaggregation Of Revenue [Line Items]
Contract liabilities				4,600			4,600		$ 11,500
VUMERITY | Biogen
Disaggregation Of Revenue [Line Items]
Contract assets				5,000			$ 5,000
Consideration expected to receive year							2022-11
Royalty
Disaggregation Of Revenue [Line Items]
Royalty revenue				35,712		112,308	$ 161,807	320,071
Royalty | AMPYRA
Disaggregation Of Revenue [Line Items]
Royalty revenue				(3,200)	$ 3,200		(3,200)
Repayment of royalty revenue				18,300			18,300
Royalty | AMPYRA | Forecast
Disaggregation Of Revenue [Line Items]
Potential additional award to be paid			$ 1,800
Royalty | AMPYRA | Subsequent Event
Disaggregation Of Revenue [Line Items]
Royalty revenue	$ 16,500
Arbitration award amount paid		$ 16,500
Royalty | VUMERITY
Disaggregation Of Revenue [Line Items]
Royalty revenue				$ 20,666		$ 18,250	$ 60,386	$ 42,866
Minimum
Disaggregation Of Revenue [Line Items]
Manufacturing Process period							10 days
Maximum
Disaggregation Of Revenue [Line Items]
Manufacturing Process period							56 days

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