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Investments - Additional Information (Details) $ in Thousands, € in Millions	3 Months Ended		9 Months Ended	12 Months Ended
	Sep. 30, 2022 USD ($)	Mar. 31, 2022 USD ($) Portfolio	Sep. 30, 2022 USD ($)	Dec. 31, 2021 USD ($)	Sep. 30, 2022 EUR (€)	Jan. 31, 2022 USD ($)
Investment Holdings [Line Items]
Aggregate estimated fair value of investments in unrealized loss position	$ 477,000		$ 477,000
Return of Fountain Healthcare Partners II, L.P. investment			$ 485
Synchronicity Pharma Inc | Convertible Promissory Notes | Investee
Investment Holdings [Line Items]
Purchase of convertible promissory notes						$ 500
Fountain Healthcare Partners II
Investment Holdings [Line Items]
Funding commitment as percentage of partnership's total funding	7.00%		7.00%		7.00%
Equity method commitment | €					€ 8.0
Number of portfolio sold | Portfolio		1
Proceeds from sale of portfolio		$ 1,000		$ 1,100
Escrow deposit		100
Gain (loss) on sale of investment	$ 500		$ 1,600
Return of Fountain Healthcare Partners II, L.P. investment		500
Fountain Healthcare Partners II | Other Assets
Investment Holdings [Line Items]
Carrying value of equity investment	6,700		$ 6,700	$ 6,100
Other (Expense) Income, Net
Investment Holdings [Line Items]
Other-than-temporary impairment charge	$ 500
Other Expense, Net | Fountain Healthcare Partners II
Investment Holdings [Line Items]
Gain (loss) on sale of investment		$ 600

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