<SEC-DOCUMENT>0001140361-23-031448-index.html : 20230626
<SEC-HEADER>0001140361-23-031448.hdr.sgml : 20230626
<ACCEPTANCE-DATETIME>20230626170015
ACCESSION NUMBER:		0001140361-23-031448
CONFORMED SUBMISSION TYPE:	DFAN14A
PUBLIC DOCUMENT COUNT:		18
FILED AS OF DATE:		20230626
DATE AS OF CHANGE:		20230626

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Alkermes plc.
		CENTRAL INDEX KEY:			0001520262
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				981007018
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		DFAN14A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-35299
		FILM NUMBER:		231043029

	BUSINESS ADDRESS:	
		STREET 1:		CONNAUGHT HOUSE
		STREET 2:		1 BURLINGTON ROAD
		CITY:			DUBLIN 4
		STATE:			L2
		ZIP:			00000
		BUSINESS PHONE:		00-353-1-772-8000

	MAIL ADDRESS:	
		STREET 1:		CONNAUGHT HOUSE
		STREET 2:		1 BURLINGTON ROAD
		CITY:			DUBLIN 4
		STATE:			L2
		ZIP:			00000

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ANTLER SCIENCE TWO PLC
		DATE OF NAME CHANGE:	20110804

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Antler Science Two Ltd
		DATE OF NAME CHANGE:	20110509

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Sarissa Capital Management LP
		CENTRAL INDEX KEY:			0001577524
		IRS NUMBER:				900924432
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		DFAN14A

	BUSINESS ADDRESS:	
		STREET 1:		660 STEAMBOAT ROAD
		CITY:			GREENWICH
		STATE:			CT
		ZIP:			06830
		BUSINESS PHONE:		203-302-2330

	MAIL ADDRESS:	
		STREET 1:		660 STEAMBOAT ROAD
		CITY:			GREENWICH
		STATE:			CT
		ZIP:			06830
</SEC-HEADER>
<DOCUMENT>
<TYPE>DFAN14A
<SEQUENCE>1
<FILENAME>brhc20054914_dfan14a.htm
<DESCRIPTION>DFAN14A
<TEXT>
Document 1 - file: brhc20054914_dfan14a.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>brhc20054914_dfan14aslide1.jpg
<TEXT>
Document 2 - file: brhc20054914_dfan14aslide1.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>brhc20054914_dfan14aslide2.jpg
<TEXT>
Document 3 - file: brhc20054914_dfan14aslide2.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>brhc20054914_dfan14aslide3.jpg
<TEXT>
Document 4 - file: brhc20054914_dfan14aslide3.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>brhc20054914_dfan14aslide4.jpg
<TEXT>
Document 5 - file: brhc20054914_dfan14aslide4.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>brhc20054914_dfan14aslide5.jpg
<TEXT>
Document 6 - file: brhc20054914_dfan14aslide5.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>brhc20054914_dfan14aslide6.jpg
<TEXT>
Document 7 - file: brhc20054914_dfan14aslide6.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>8
<FILENAME>brhc20054914_dfan14aslide7.jpg
<TEXT>
Document 8 - file: brhc20054914_dfan14aslide7.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>9
<FILENAME>brhc20054914_dfan14aslide8.jpg
<TEXT>
Document 9 - file: brhc20054914_dfan14aslide8.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>10
<FILENAME>brhc20054914_dfan14aslide9.jpg
<TEXT>
Document 10 - file: brhc20054914_dfan14aslide9.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>11
<FILENAME>brhc20054914_dfan14aslide10.jpg
<TEXT>
Document 11 - file: brhc20054914_dfan14aslide10.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>12
<FILENAME>brhc20054914_dfan14aslide11.jpg
<TEXT>
Document 12 - file: brhc20054914_dfan14aslide11.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>13
<FILENAME>brhc20054914_dfan14aslide12.jpg
<TEXT>
Document 13 - file: brhc20054914_dfan14aslide12.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>14
<FILENAME>brhc20054914_dfan14aslide13.jpg
<TEXT>
Document 14 - file: brhc20054914_dfan14aslide13.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>15
<FILENAME>brhc20054914_dfan14aslide14.jpg
<TEXT>
Document 15 - file: brhc20054914_dfan14aslide14.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>16
<FILENAME>brhc20054914_dfan14aslide15.jpg
<TEXT>
Document 16 - file: brhc20054914_dfan14aslide15.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>17
<FILENAME>brhc20054914_dfan14aslide16.jpg
<TEXT>
Document 17 - file: brhc20054914_dfan14aslide16.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>18
<FILENAME>brhc20054914_dfan14aslide17.jpg
<TEXT>
Document 18 - file: brhc20054914_dfan14aslide17.jpg

</DOCUMENT>
</SEC-DOCUMENT>