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Share-based Compensation - Schedule of Share-based Compensation Expense from Continuing and Discontinued Operations (Details) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
Share-based compensation Expense |  |  |
Total share-based compensation expense | $ 96,637 | $ 100,905 | $ 94,254
Continuing Operations |  |  |
Share-based compensation Expense |  |  |
Total share-based compensation expense | 96,637 | 92,717 | 87,677
Discontinued Operations |  |  |
Share-based compensation Expense |  |  |
Total share-based compensation expense |  | 8,188 | 6,577
Cost of goods manufactured and sold | Continuing Operations |  |  |
Share-based compensation Expense |  |  |
Total share-based compensation expense | 5,798 | 11,353 | 10,284
Research and development | Continuing Operations |  |  |
Share-based compensation Expense |  |  |
Total share-based compensation expense | 28,085 | 25,753 | 23,289
Research and development | Discontinued Operations |  |  |
Share-based compensation Expense |  |  |
Total share-based compensation expense |  | 3,255 | 4,652
Selling, general and administrative | Continuing Operations |  |  |
Share-based compensation Expense |  |  |
Total share-based compensation expense | $ 62,754 | 55,611 | 54,104
Selling, general and administrative | Discontinued Operations |  |  |
Share-based compensation Expense |  |  |
Total share-based compensation expense |  | $ 4,933 | $ 1,925

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- Definition Amount of expense for award under share-based payment arrangement. Excludes amount capitalized. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 14.F) -Publisher FASB -URI https://asc.fasb.org/1943274/2147479830/718-10-S99-1 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (h)(1)(i) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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