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Share-based Compensation (Tables) | 12 Months Ended
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Dec. 31, 2024
Schedule of Share-based Compensation Expense from Continuing and Discontinued Operations | The following table presents share-based compensation expense from continuing and discontinued operations included in the Company’s consolidated statements of operations and comprehensive income (loss):
|  | Year Ended December 31, |
(In thousands) |  | 2024 |  |  | 2023 |  |  | 2022 |
Cost of goods manufactured and sold |  | $ | 5,798 |  |  | $ | 11,353 |  |  | $ | 10,284 |
Research and development |  |  | 28,085 |  |  |  | 25,753 |  |  |  | 23,289 |
Selling, general and administrative |  |  | 62,754 |  |  |  | 55,611 |  |  |  | 54,104 |
Share-based compensation expense from continuing operations |  |  | 96,637 |  |  |  | 92,717 |  |  |  | 87,677 |
Cost of goods manufactured and sold |  |  | — |  |  |  | — |  |  |  | — |
Research and development |  |  | — |  |  |  | 3,255 |  |  |  | 4,652 |
Selling, general and administrative |  |  | — |  |  |  | 4,933 |  |  |  | 1,925 |
Share-based compensation expense from discontinued operations |  |  | — |  |  |  | 8,188 |  |  |  | 6,577 |
Total share-based compensation expense |  | $ | 96,637 |  |  | $ | 100,905 |  |  | $ | 94,254 |
Schedule of Stock Option Activity | A summary of stock option activity is presented in the following table:
|  | Number of |  |  | Weighted Average |
|  | Shares |  |  | Exercise Price |
Outstanding, January 1, 2024 |  |  | 18,139,903 |  |  | $ | 32.28 |
Granted |  |  | 2,615,357 |  |  | $ | 29.48 |
Exercised |  |  | (1,328,189 | ) |  | $ | 20.76 |
Expired |  |  | (1,427,409 | ) |  | $ | 46.72 |
Forfeited |  |  | (521,043 | ) |  | $ | 26.65 |
Outstanding, December 31, 2024 |  |  | 17,478,619 |  |  | $ | 31.73 |
Exercisable, December 31, 2024 |  |  | 10,979,663 |  |  | $ | 34.53 |
Time-based RSU Awards |
Summary of RSU Activity | A summary of time-based RSU activity is presented in the following table:
|  |  |  |  | Weighted Average |
|  | Number of Shares |  |  | Grant Date Fair Value |
Unvested, January 1, 2024 |  |  | 5,657,578 |  |  | $ | 24.18 |
Granted |  |  | 2,260,345 |  |  | $ | 29.51 |
Forfeited |  |  | (775,415 | ) |  | $ | 26.43 |
Vested |  |  | (2,237,302 | ) |  | $ | 23.05 |
Unvested, December 31, 2024 |  |  | 4,905,206 |  |  | $ | 26.80 |
Performance-based RSUs Awards |
Summary of RSU Activity | A summary of performance-based RSU activity is presented in the following table:
|  |  |  |  | Weighted Average |
|  | Number of Shares |  |  | Grant Date Fair Value |
Unvested, January 1, 2024 |  |  | 1,546,357 |  |  | $ | 27.95 |
Granted |  |  | 498,120 |  |  | $ | 32.46 |
Forfeited |  |  | (172,576 | ) |  | $ | 25.88 |
Vested |  |  | (536,243 | ) |  | $ | 22.21 |
Unvested, December 31, 2024 |  |  | 1,335,658 |  |  | $ | 32.13 |

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