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Share-based Compensation (Tables)

12 Months Ended

Dec. 31, 2024

Schedule of Share-based Compensation Expense from Continuing and Discontinued Operations

The following table presents share-based compensation expense from continuing and discontinued operations included in the Company’s consolidated statements of operations and comprehensive income (loss):

		Year Ended December 31,
(In thousands)		2024				2023				2022
Cost of goods manufactured and sold		$	5,798			$	11,353			$	10,284
Research and development			28,085				25,753				23,289
Selling, general and administrative			62,754				55,611				54,104
Share-based compensation expense from continuing operations			96,637				92,717				87,677
Cost of goods manufactured and sold			—				—				—
Research and development			—				3,255				4,652
Selling, general and administrative			—				4,933				1,925
Share-based compensation expense from discontinued operations			—				8,188				6,577
Total share-based compensation expense		$	96,637			$	100,905			$	94,254

Schedule of Stock Option Activity

A summary of stock option activity is presented in the following table:

		Number of				Weighted Average
		Shares				Exercise Price
Outstanding, January 1, 2024			18,139,903			$	32.28
Granted			2,615,357			$	29.48
Exercised			(1,328,189	)		$	20.76
Expired			(1,427,409	)		$	46.72
Forfeited			(521,043	)		$	26.65
Outstanding, December 31, 2024			17,478,619			$	31.73
Exercisable, December 31, 2024			10,979,663			$	34.53

Time-based RSU Awards

Summary of RSU Activity

A summary of time-based RSU activity is presented in the following table:

						Weighted Average
		Number of Shares				Grant Date Fair Value
Unvested, January 1, 2024			5,657,578			$	24.18
Granted			2,260,345			$	29.51
Forfeited			(775,415	)		$	26.43
Vested			(2,237,302	)		$	23.05
Unvested, December 31, 2024			4,905,206			$	26.80

Performance-based RSUs Awards

Summary of RSU Activity

A summary of performance-based RSU activity is presented in the following table:

						Weighted Average
		Number of Shares				Grant Date Fair Value
Unvested, January 1, 2024			1,546,357			$	27.95
Granted			498,120			$	32.46
Forfeited			(172,576	)		$	25.88
Vested			(536,243	)		$	22.21
Unvested, December 31, 2024			1,335,658			$	32.13

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