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v3.26.1

Segment Reporting - Summary of Significant Segment Expenses (Details) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2026 | Mar. 31, 2026 | Jun. 30, 2025 | Mar. 31, 2025 | Jun. 30, 2026 | Jun. 30, 2025
REVENUES: |  |  |  |  |  |  |
Total revenues |  | $ 496,009 |  | $ 390,657 |  | $ 888,920 | $ 697,167
EXPENSES: |  |  |  |  |  |  |
Cost of goods manufactured and sold (exclusive of amortization of acquired intangible assets shown below) |  | 98,112 |  | 49,460 |  | 159,690 | 98,657
Development programs: |  |  |  |  |  |  |
Alixorexton |  | 28,797 |  | 23,795 |  | 54,294 | 41,649
LYBALVI |  | 4,939 |  | 5,050 |  | 9,388 | 8,901
LUMRYZ |  | 4,710 |  | 0 |  | 7,633 | 0
Other orexin programs |  | 15,090 |  | 2,709 |  | 21,944 | 6,178
Other external R&D expenses |  | 13,832 |  | 7,880 |  | 24,938 | 15,384
Total external R&D expenses |  | 67,368 |  | 39,434 |  | 118,197 | 72,112
Internal R&D expenses: |  |  |  |  |  |  |
Employee-related |  | 37,013 |  | 30,651 |  | 80,627 | 62,005
Occupancy |  | 3,335 |  | 3,308 |  | 6,599 | 6,455
Depreciation |  | 1,850 |  | 1,474 |  | 3,537 | 2,942
Other internal R&D expenses |  | 3,354 |  | 2,503 |  | 7,305 | 5,673
Total internal R&D expenses |  | 45,552 |  | 37,936 |  | 98,068 | 77,075
R&D expenses |  | 112,920 |  | 77,370 |  | 216,265 | 149,187
Selling, general and administrative expenses: |  |  |  |  |  |  |
Selling and marketing expense |  | 154,364 |  | 121,175 |  | 309,276 | 244,109
General and administrative expense |  | 63,261 |  | 49,674 |  | 172,942 | 98,444
Total selling, general and administrative expense |  | 217,625 |  | 170,849 |  | 482,218 | 342,553
Other segment (expense) income | [1] | (66,851) |  | (5,880) |  | (96,726) | 2,792
NET (LOSS) INCOME |  | $ 501 | $ (66,480) | $ 87,098 | $ 22,464 | $ (65,979) | $ 109,562
[1] | “Other segment (expense) income” during the three and six months ended June 30, 2026 and 2025, includes “Amortization of acquired intangible assets”, “Change in fair value of contingent consideration”, “Total other (expense) income, net” and “Income tax provision (benefit)”.

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