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RELATED PARTY TRANSACTIONS (Details Narrative) - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Related Party Transaction [Line Items] |  |  |
Other research and development | $ 96,886,134 | $ 66,489,820 | $ 43,445,817
Prepaid Research And Development | 8,055,486 | 5,678,755 |
Average Annual Rental Payments |  | 1,100,000 |
Lfb Group [Member] |  |  |
Related Party Transaction [Line Items] |  |  |
Other research and development | 2,300,000 | 8,100,000 |
Accounts Payable | 0 | 400,000 |
Costs and Expenses, Related Party |  | 8,100,000 |
Prepaid Research And Development | 0 | 1,300,000 |
Shared Services Agreement [Member] |  |  |
Related Party Transaction [Line Items] |  |  |
Costs and Expenses, Related Party | 1,200,000 | 800,000 |
Opus [Member] |  |  |
Related Party Transaction [Line Items] |  |  |
Costs and Expenses, Related Party |  | 300,000 |
JBET Agreement [Member] |  |  |
Related Party Transaction [Line Items] |  |  |
Accounts Payable | $ 300,000 | $ 800,000 |

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