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LICENSE AGREEMENTS (Details Narrative) - USD ($) | 1 Months Ended | 12 Months Ended |  |
--- | --- | --- | --- | ---
Jun. 23, 2014 | Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015 | Dec. 31, 2012 | Dec. 31, 2014 | Dec. 31, 2013
License Agreement [Line Items] |  |  |  |  |  |  |
License revenue |  | $ 152,381 | $ 152,381 | $ 152,381 |  |  |
Deferred Revenue |  | 1,219,000 | 1,371,000 | 1,524,000 |  | $ 1,676,000 | $ 1,829,000
Income taxes |  | 0 | $ 0 | 0 |  |  |
Royalty payment Effective Percentage |  |  | 6.00% |  |  |  |
Other Research and Development Expense |  | $ 96,886,134 | $ 66,489,820 | $ 43,445,817 |  |  |
JBET Agreement [Member] |  |  |  |  |  |  |
License Agreement [Line Items] |  |  |  |  |  |  |
Additional Amount Receivable On Achievement Of Pre Specified Milestones |  |  | $ 177,000,000 |  |  |  |
Opus [Member] |  |  |  |  |  |  |
License Agreement [Line Items] |  |  |  |  |  |  |
Royalty payment Effective Percentage |  |  | 1.00% |  |  |  |
Licensing Agreements [Member] |  |  |  |  |  |  |
License Agreement [Line Items] |  |  |  |  |  |  |
Upfront Fee Received From Sub License |  |  |  |  | $ 2,000,000 |  |
Income taxes |  |  |  |  | $ 300,000 |  |
Licensing Agreements IRAK4[Member] |  |  |  |  |  |  |
License Agreement [Line Items] |  |  |  |  |  |  |
Stock Issued During Period, Shares, Issued for Services | 125,000 |  |  |  |  |  |
Maximum Potential Payments Payable | $ 207,000,000 |  |  |  |  |  |
Royalty payment Effective Percentage | 6.00% |  |  |  |  |  |
Maximum sales for royalty expense | $ 1,000,000,000 |  |  |  |  |  |

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