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Consolidated Statements of Equity - USD ($) | Common Stock [Member] | Contingently Issuable Share [Member] | Additional Paid-in Capital [Member] | Treasury Stock [Member] | Accumulated Deficit [Member] | Total
--- | --- | --- | --- | --- | --- | ---
Balance at Dec. 31, 2014 | $ 44,974 |  | $ 175,476,521 | $ (234,337) | $ (95,185,280) | $ 80,101,884
Balance (in shares) at Dec. 31, 2014 | 44,974,248 | 6 |  | 41,309 |  |
Issuance of common stock in connection with exercise of warrants | $ 2,946 |  | 1,064,393 |  |  | 1,067,339
Issuance of common stock in connection with exercise of warrants (in shares) | 2,946,703 |  |  |  |  |
Issuance of common stock in connection with cashless exercise of warrants | $ 3 |  | (3) |  |  | 0
Issuance of common stock in connection with cashless exercise of warrants (in shares) | 2,915 |  |  |  |  |
Issuance of common stock in connection with conversion of notes payable | $ 1 |  | 6,924 |  |  | 6,925
Issuance of common stock in connection with conversion of notes payable (in shares) | 522 |  |  |  |  |
Issuance of restricted stock | $ 1,993 |  | (1,993) |  |  | 0
Issuance of restricted stock (in shares) | 1,992,535 |  |  |  |  |
Forfeiture of restricted stock | $ (31) |  | 31 |  |  | 0
Forfeiture of restricted stock (in shares) | (31,166) |  |  |  |  |
Issuance of common stock to related party for cash (See Note 9) | $ 115 |  | 749,890 |  |  | 750,005
Issuance of common stock to related party for cash (See Note 9) (in shares) | 114,855 |  |  |  |  |
Compensation in respect of restricted stock granted to employees, directors and consultants |  |  | 15,697,092 |  |  | 15,697,092
Issuance of common stock in At the Market offering | $ 4,094 |  | 66,894,609 |  |  | 66,898,703
Issuance of common stock in At the Market offering (in shares) | 4,094,498 |  |  |  |  |
Net loss |  |  |  |  | (62,948,646) | (62,948,646)
Balance at Dec. 31, 2015 | $ 54,095 |  | 259,887,464 | $ (234,337) | (158,133,926) | 101,573,302
Balance (in shares) at Dec. 31, 2015 | 54,095,110 | 6 |  | 41,309 |  |
Issuance of common stock in connection with exercise of warrants | $ 273 |  | 617,969 |  |  | 618,242
Issuance of common stock in connection with exercise of warrants (in shares) | 273,370 |  |  |  |  |
Issuance of common stock in connection with conversion of notes payable | $ 4 |  | 33,013 |  |  | 33,017
Issuance of common stock in connection with conversion of notes payable (in shares) | 3,710 |  |  |  |  |
Issuance of restricted stock | $ 1,925 |  | (1,925) |  |  | 0
Issuance of restricted stock (in shares) | 1,924,639 |  |  |  |  |
Forfeiture of restricted stock | $ (47) |  | 47 |  |  | 0
Forfeiture of restricted stock (in shares) | (46,773) |  |  |  |  |
Issuance of common stock in At-the-Market offering (net of offering costs) | $ 570 |  | 4,385,566 |  |  | 4,386,136
Issuance of common stock in At-the-Market offering (net of offering costs) (in shares) | 570,366 |  |  |  |  |
Compensation in respect of restricted stock granted to employees, directors and consultants |  |  | 7,509,999 |  |  | 7,509,999
Adjustment to contingently issuable shares |  | $ (6) | 6 |  |  | 0
Net loss |  |  |  |  | (78,252,894) | (78,252,894)
Balance at Dec. 31, 2016 | $ 56,820 | 0 | 272,432,139 | $ (234,337) | (236,386,820) | 35,867,802
Balance (in shares) at Dec. 31, 2016 | 56,820,422 |  |  | 41,309 |  |
Issuance of common stock in connection with exercise of warrants | $ 888 |  | 2,142,197 |  |  | 2,143,085
Issuance of common stock in connection with exercise of warrants (in shares) | 887,585 |  |  |  |  |
Issuance of restricted stock | $ 1,837 |  | (1,837) |  |  |
Issuance of restricted stock (in shares) | 1,836,511 |  |  |  |  |
Forfeiture of restricted stock | $ (54) |  | 54 |  |  |
Forfeiture of restricted stock (in shares) | (53,875) |  |  |  |  |
Issuance of common stock in At-the-Market offering (net of offering costs) | $ 5,897 |  | 53,634,115 |  |  | 53,640,012
Issuance of common stock in At-the-Market offering (net of offering costs) (in shares) | 5,897,436 |  |  |  |  |
Compensation in respect of restricted stock granted to employees, directors and consultants |  |  | 15,945,284 |  |  | 15,945,284
Issuance of common stock in At the Market offering | $ 7,794 |  | 77,865,090 |  |  | 77,872,884
Issuance of common stock in At the Market offering (in shares) | 7,793,671 |  |  |  |  |
Net loss |  |  |  |  | (118,476,012) | (118,476,012)
Balance at Dec. 31, 2017 | $ 73,182 | $ 0 | $ 422,017,042 | $ (234,337) | $ (354,862,832) | $ 66,993,055
Balance (in shares) at Dec. 31, 2017 | 73,181,750 |  |  | 41,309 |  |

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