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QUARTERLY FINANCIAL INFORMATION (Tables) | 12 Months Ended
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Dec. 31, 2017
Table Text Block Supplement [Abstract] |
Schedule of Quarterly Financial Information |
|  | 3 Months Ended |
|  | March 31, 2017 |  |  | June 30, 2017 |  |  | September 30, 2017 |  |  | December 31, 2017 |
License revenue |  | $ | 38,095 |  |  | $ | 38,095 |  |  | $ | 38,096 |  |  | $ | 38,095 |
Total costs and expenses |  |  | 27,704,517 |  |  |  | 28,463,466 |  |  |  | 31,623,323 |  |  |  | 31,072,826 |
Net loss |  | $ | (27,727,509 | ) |  | $ | (28,353,084 | ) |  | $ | (31,535,652 | ) |  | $ | (30,859,767 | )
Basic and diluted net loss per common share |  | $ | (0.52 | ) |  | $ | (0.45 | ) |  | $ | (0.48 | ) |  | $ | (0.46 | )
|  | 3 Months Ended |
|  | March 31, 2016 |  |  | June 30, 2016 |  |  | September 30, 2016 |  |  | December 31, 2016 |
License revenue |  | $ | 38,095 |  |  | $ | 38,095 |  |  | $ | 38,096 |  |  | $ | 38,095 |
Total costs and expenses |  |  | 14,030,251 |  |  |  | 16,061,538 |  |  |  | 24,963,567 |  |  |  | 24,066,153 |
Net loss |  | $ | (13,848,662 | ) |  | $ | (15,899,062 | ) |  | $ | (24,831,027 | ) |  | $ | (23,674,143 | )
Basic and diluted net loss per common share |  | $ | (0.28 | ) |  | $ | (0.33 | ) |  | $ | (0.50 | ) |  | $ | (0.48 | )

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- Definition Tabular disclosure of quarterly financial data. Includes, but is not limited to, financial information for fiscal quarters, cumulative effect of a change in accounting principle and earnings per share data. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 270 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (a)-(j) -URI http://asc.fasb.org/extlink&oid=84173487&loc=d3e1280-108306 + Details
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