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Condensed Consolidated Statement of Stockholders' Equity - 6 months ended Jun. 30, 2018 - USD ($) $ in Thousands | Common Stock [Member] | Additional Paid-in Capital [Member] | Treasury Stock [Member] | Accumulated Deficit [Member] | Total
--- | --- | --- | --- | --- | ---
Balance (in shares) at Dec. 31, 2017 | 73,181,750 |  | 41,309 |  |
Balance at Dec. 31, 2017 | $ 73 | $ 422,017 | $ (234) | $ (354,863) | $ 66,993
Issuance of restricted stock (in shares) | 1,420,511 |  |  |  |
Issuance of restricted stock | $ 1 | (1) |  |  |
Forfeiture of restricted stock (in shares) | (130,661) |  |  |  |
Issuance of common stock in At-the-Market offerings (net of offering costs of $1.9 million) (in shares) | 7,733,949 |  |  |  |
Issuance of common stock in At-the-Market offerings (net of offering costs of $1.9 million) | $ 8 | 104,445 |  |  | 104,453
Compensation in respect of restricted stock granted to employees, directors and consultants |  | 11,601 |  |  | 11,601
Shares issued in connection with in-licensing agreements (in shares) | 333,868 |  |  |  |
Shares issued in connection with in-licensing agreements |  | 4,000 |  |  | 4,000
Net loss |  |  |  | (85,671) | (85,671)
Balance (in shares) at Jun. 30, 2018 | 82,539,417 |  | 41,309 |  |
Balance at Jun. 30, 2018 | $ 82 | $ 542,062 | $ (234) | $ (440,534) | $ 101,376

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