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ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Details Narrative) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended |
--- | --- | --- | ---
Jun. 30, 2018 | Jun. 30, 2017 | Jun. 30, 2018 | Jun. 30, 2017 | Dec. 31, 2017
Accounting Policies [Abstract] |  |  |  |  |
Accumulated deficit | $ (440,534) |  | $ (440,534) |  | $ (354,863)
Restricted cash and investments | 1,200 |  | 1,200 |  | 600
Prepaid research and development | $ 8,890 |  | $ 8,890 |  | $ 8,056
Antidilutive securities excluded from computation of earnings per share, amount | 5,165,890 | 4,290,943 | 5,165,890 | 4,290,943 |

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