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Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2018 | Jun. 30, 2017
CASH FLOWS FROM OPERATING ACTIVITIES: |  |
Net loss | $ (85,671) | $ (56,081)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Noncash stock compensation expense | 11,601 | 7,485
Noncash licensing expense | 4,000 | 0
Depreciation | 41 | 41
Amortization of premium on investment securities | (9) | 45
Change in fair value of notes payable | 82 | 84
Changes in assets and liabilities: |  |
Increase in other current assets | (1,213) | (4,252)
Decrease in leasehold interest | 53 | 75
Decrease in accrued interest receivable | 22 | 41
Decrease in other assets | 0 | 395
Increase in accounts payable and accrued expenses | 8,898 | 3,068
Increase in deferred rent | 46 | 45
Decrease in deferred revenue | (76) | (76)
Net cash used in operating activities | (62,226) | (49,130)
CASH FLOWS FROM INVESTING ACTIVITIES: |  |
Purchases of equipment | (58) | (2)
Investment in held-to-maturity securities | (6,965) | 0
Proceeds from maturity of short-term securities | 14,400 | 11,000
Net cash provided by investing activities | 7,377 | 10,998
CASH FLOWS FROM FINANCING ACTIVITIES: |  |
Proceeds from the exercise of warrants | 0 | 2,143
Proceeds from sale of common stock, net | 104,453 | 88,562
Net cash provided by financing activities | 104,453 | 90,705
NET INCREASE IN CASH, CASH EQUIVALENTS AND RESTRICTED CASH | 49,604 | 52,573
CASH, CASH EQUIVALENTS AND RESTRICTED CASH AT BEGINNING OF PERIOD | 57,305 | 25,614
CASH, CASH EQUIVALENTS AND RESTRICTED CASH AT END OF PERIOD | 106,909 | 78,187
Reconciliation to amounts on consolidated balance sheets: |  |
Total cash, cash equivalents and restricted cash | 106,909 | 25,614
NONCASH TRANSACTIONS |  |
Accrued financing costs | 0 | 234
Reclassification of deferred financing costs to additional paid-in capital | $ 0 | $ (3)

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