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QUARTERLY FINANCIAL INFORMATION | 12 Months Ended
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Dec. 31, 2018
Disclosure Text Block [Abstract] |
QUARTERLY FINANCIAL INFORMATION |
(in thousands) |  | 3 Months Ended |
|  | March 31, 2018 |  |  | June 30, 2018 |  |  | September 30, 2018 |  |  | December 31, 2018 |
License revenue |  | $ | 38 |  |  | $ | 38 |  |  | $ | 38 |  |  | $ | 38 |
Total costs and expenses |  |  | 40,615 |  |  |  | 44,383 |  |  |  | 34,366 |  |  |  | 54,188 |
Net loss |  | $ | (41,529 | ) |  | $ | (44,142 | ) |  | $ | (33,951 | ) |  | $ | (53,861 | )
Basic and diluted net loss per common share |  | $ | (0.59 | ) |  | $ | (0.59 | ) |  | $ | (0.43 | ) |  | $ | (0.68 | )
(in thousands) |  | 3 Months Ended |
|  | March 31, 2017 |  |  | June 30, 2017 |  |  | September 30, 2017 |  |  | December 31, 2017 |
License revenue |  | $ | 38 |  |  | $ | 38 |  |  | $ | 38 |  |  | $ | 38 |
Total costs and expenses |  |  | 27,704 |  |  |  | 28,463 |  |  |  | 31,623 |  |  |  | 31,073 |
Net loss |  | $ | (27,727 | ) |  | $ | (28,353 | ) |  | $ | (31,536 | ) |  | $ | (30,860 | )
Basic and diluted net loss per common share |  | $ | (0.52 | ) |  | $ | (0.45 | ) |  | $ | (0.48 | ) |  | $ | (0.46 | )

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- Definition The entire disclosure for quarterly financial data. Includes, but is not limited to, tabular presentation of financial information for fiscal quarters, effect of year-end adjustments, and an explanation of matters or transactions that affect comparability of the information. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 270 -URI http://asc.fasb.org/topic&trid=2126967 + Details
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