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ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Details Narrative) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Accounting Policies [Abstract]      
Accumulated deficit $ (528,345) $ (354,863)  
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount 6,528,932 4,835,706 8,033,779
Restricted Cash and Investments $ 600 $ 600  
Prepaid Manufacturing $ 9,700 $ 8,100