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QUARTERLY FINANCIAL INFORMATION (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2017
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Table Text Block Supplement [Abstract]                      
License revenue $ 38 $ 38 $ 38 $ 38 $ 38 $ 38 $ 38 $ 38      
Total costs and expenses 54,188 34,366 44,383 40,615 31,073 31,623 28,463 27,704 $ 174,552 $ 118,864 $ 79,121
Net loss $ (53,861) $ (33,951) $ (44,142) $ (41,529) $ (30,860) $ (31,536) $ (28,353) $ (27,727)      
Basic and diluted net loss per common share $ (0.68) $ (0.43) $ (0.59) $ (0.59) $ (0.46) $ (0.48) $ (0.45) $ (0.52) $ (2.30) $ (1.91) $ (1.60)