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Condensed Consolidated Balance Sheets - USD ($)
$ in Thousands
Sep. 30, 2021
Dec. 31, 2020
Current assets:    
Cash and cash equivalents $ 326,512 $ 553,439
Short-term investment securities 30,338 51,987
Accounts receivable, net 1,384  
Prepaid research and development 11,043 5,231
Other current assets 2,502 1,083
Total current assets 371,779 611,740
Restricted cash 1,263 1,259
Long-term investment securities 24,550  
Right of use assets 8,804 9,312
Leasehold interest, net 1,892 2,051
Equipment, net 600 481
Goodwill 799 799
Total assets 409,687 625,642
Current liabilities:    
Accounts payable and accrued expenses 44,702 37,014
Other current liabilities 12,628 18,236
Loan payable - current portion 15,999 22,179
Lease liability - current portion 1,468 1,669
Accrued compensation 12,858 8,456
Total current liabilities 87,655 87,554
Deferred revenue, net of current portion 495 610
Loan payable - non-current   7,716
Lease liability - non-current 10,020 10,412
Total liabilities 98,170 106,292
Commitments and contingencies
Stockholders' equity:    
Common stock, $0.001 par value per share (175,000,000 shares authorized, 142,984,448 and 140,617,606 shares issued, 142,943,139 and 140,576,297 shares outstanding at September 30, 2021 and December 31, 2020, respectively) 143 141
Additional paid-in capital 1,546,967 1,500,040
Treasury stock, at cost, 41,309 shares at September 30, 2021 and December 31, 2020 (234) (234)
Accumulated deficit (1,235,359) (980,597)
Total stockholders' equity 311,517 519,350
Total liabilities and stockholders' equity $ 409,687 $ 625,642