Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	9 Months Ended
Sep. 30, 2021	Sep. 30, 2020
CASH FLOWS FROM OPERATING ACTIVITIES
Net loss	$ (254,763)	$ (191,163)
Adjustments to reconcile net loss to net cash used in operating activities:
Noncash stock compensation expense	46,918	46,768
Depreciation and amortization	202	105
Amortization of premium on investment securities	421
Amortization of premium on investment securities		(75)
Amortization of debt issuance costs	694	694
Amortization of leasehold interest	159	163
Noncash change in lease liability and right of use asset	1,422	1,364
Change in fair value of notes payable	(315)	286
Changes in assets and liabilities:
(Increase) decrease in other current assets	(7,255)	2,503
Increase in accounts receivable	(1,384)
Increase (decrease) in accounts payable and accrued expenses	12,090	5,893
Decrease in lease liabilities	(1,507)	(1,360)
Decrease in other liabilities	(5,293)	(27,545)
Decrease in deferred revenue	(114)	(114)
Net cash used in operating activities	(208,725)	(162,481)
CASH FLOWS FROM INVESTING ACTIVITIES
Proceeds from maturity of short-term securities	40,000	35,250
Investment in held-to-maturity securities	(43,299)	(7,482)
Purchases of equipment	(321)	(202)
Net cash (used in) provided by investing activities	(3,620)	27,566
CASH FLOWS FROM FINANCING ACTIVITIES
Payment of loan payable	(14,590)
Proceeds from sale of common stock, net		276,303
Proceeds from exercise of options	216	135
Offering costs paid	(204)
Net cash (used in) provided by financing activities	(14,578)	276,438
NET (DECREASE) INCREASE IN CASH, CASH EQUIVALENTS AND RESTRICTED CASH	(226,923)	141,523
CASH, CASH EQUIVALENTS AND RESTRICTED CASH AT BEGINNING OF PERIOD	554,698	113,888
CASH, CASH EQUIVALENTS AND RESTRICTED CASH AT END OF PERIOD	$ 327,775	$ 255,411

The change in fair value of notes payable during the period.

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