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Note 8 - Leases (Details Textual) $ in Thousands | 1 Months Ended | 3 Months Ended |  |  |  |
--- | --- | --- | --- | --- | --- | ---
Oct. 31, 2021 USD ($) | Oct. 31, 2014 USD ($) ft² | Mar. 31, 2025 USD ($) | Dec. 31, 2024 USD ($) | Mar. 31, 2024 USD ($) | Dec. 31, 2021 | Feb. 28, 2019
Restricted Cash |  |  | $ 1,302 |  |  | $ 1,289 |  |
Operating Lease, Liability |  |  | 8,976 | [1] | $ 9,290 |  |  |
Operating Lease, Right-of-Use Asset |  |  | $ 6,927 |  | $ 7,151 |  |  |
Operating Lease, Weighted Average Remaining Lease Term (Year) |  |  | 5 years 4 months 24 days |  |  |  |  |
Operating Lease, Weighted Average Discount Rate, Percent |  |  | 10.04% |  |  |  |  | 10.25%
Operating Lease, Payments |  |  | $ 500 |  |  |  |  |
The North Carolina Lease [Member] |  |  |  |  |  |  |  |
Average Annual Rental Payments | $ 200 |  |  |  |  |  |  |
Operating Lease, Expense |  |  | $ 100 |  |  |  |  |
Operating Lease, Weighted Average Discount Rate, Percent |  |  |  |  |  |  | 5.65% |
Office Agreement with Fortress Biotech [Member] |  |  |  |  |  |  |  |
Percentage of Occupancy |  | 45.00% |  |  |  |  |  |
Area of Real Estate Property (Square Foot) | ft² |  | 24,000 |  |  |  |  |  |
Lessee, Operating Lease, Term of Contract (Year) |  | 15 years |  |  |  |  |  |
Average Annual Rental Payments |  | $ 1,800 |  |  |  |  |  |
Office Agreement with Fortress Biotech [Member] | Deposit for Office Agreement [Member] |  |  |  |  |  |  |  |
Restricted Cash |  | $ 1,300 |  |  |  |  |  |
Office Agreement [Member] |  |  |  |  |  |  |  |
Lessee, Operating Lease, Renewal Term (Year) | 5 years |  | 2 years |  |  |  |  |
Operating Lease, Liability |  |  | $ 9,000 |  |  |  |  |
Operating Lease, Right-of-Use Asset |  |  | $ 6,900 |  |  |  |  |
Office Agreement [Member] | Minimum [Member] |  |  |  |  |  |  |  |
Lessee, Operating Lease, Remaining Lease Term (Year) |  |  | 2 years |  |  |  |  |
Office Agreement [Member] | Maximum [Member] |  |  |  |  |  |  |  |
Lessee, Operating Lease, Remaining Lease Term (Year) |  |  | 6 years |  |  |  |  |
[1] | As our leases do not provide an implicit rate, we use our incremental borrowing rate based on the information available at commencement date and considering the term of the lease to determine the present value of lease payments. We used the incremental borrowing rate of 10.25% on February 28, 2019, for operating leases that commenced prior to that date through December 31, 2021. We used an incremental borrowing rate of 5.65% for the NC lease.

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