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Investment in Subsidiaries - Additional Information (Detail) (USD $) | 1 Months Ended | 12 Months Ended |  |  | 12 Months Ended |  |  |  |  |  | 12 Months Ended |  | 12 Months Ended |
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Aug. 10, 2012 | Sep. 30, 2012 | Sep. 30, 2011 | Nov. 26, 2008 | Jan. 31, 2011 Preferred Class B and C [Member] | Sep. 30, 2010 Calando Pharmaceuticals, Inc. [Member] | Sep. 30, 2012 Calando Pharmaceuticals, Inc. [Member] | Jan. 31, 2011 Calando Pharmaceuticals, Inc. [Member] | Jun. 23, 2009 Calando Pharmaceuticals, Inc. [Member] | Nov. 26, 2008 Calando Pharmaceuticals, Inc. [Member] | Apr. 17, 2008 Calando Pharmaceuticals, Inc. [Member] | Sep. 30, 2011 Ablaris Therapeutics, Inc. [Member] | Sep. 30, 2012 Ablaris Therapeutics, Inc. [Member] | Sep. 30, 2012 Nanotope, Inc [Member] | Sep. 30, 2012 Leonardo Biosystems Inc [Member]
Schedule of Investments [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Ownership percentage in subsidiary |  | 100.00% |  |  |  |  |  |  |  |  |  |  |  |  |
Aggregate investment in subsidiary through equity and debt |  |  |  |  |  |  |  |  |  |  | $ 23,200,000 |  |  |  |
Unsecured Convertible Promissory Note Agreements |  |  |  | 2,500,000 |  |  |  |  |  | 2,500,000 |  |  |  |  |
Investment in Notes offering |  |  |  | 200,000 |  |  |  |  |  | 200,000 |  |  |  |  |
Additional investment in Notes offering |  |  |  | 600,000 |  |  |  |  |  | 600,000 |  |  |  |  |
Principal amount of note which not converted into shares |  |  |  |  |  |  |  |  | 500,000 |  |  |  |  |  |
Conversion of Notes and accrued interest into share |  |  |  |  |  |  |  |  | 2,950 |  |  |  |  |  |
Issuance and sold of Common Stock | 2,260,869 |  |  |  |  | 122,000 |  |  |  |  |  |  |  |  |
Issuance of warrants |  |  |  |  |  | 26,400 |  |  |  |  |  |  |  |  |
Investment in preferred stock |  |  |  |  | 9,100,000 |  |  |  |  |  |  | 1,300,000 |  |  |
Cash investment in subsidiary |  |  |  |  |  |  |  | 1,000,000 |  |  |  |  |  |  |
Investment in subsidiary through conversion of intercompany debt |  |  |  |  |  |  |  | 8,100,000 |  |  |  |  |  |  |
Amount owed by subsidiary |  |  |  |  |  |  | 3,100,000 |  |  |  |  |  |  |  | 547,000
Stated percentage of notes and advances |  |  |  |  |  |  | 8.00% |  |  |  |  |  |  |  |
Percentage of outstanding shares |  |  |  |  |  |  | 79.00% |  |  |  |  |  | 64.00% | 23.00% | 3.00%
Percentage of investment ownership |  |  |  |  |  |  | 76.00% |  |  |  |  |  | 64.00% | 19.00% |
Aggregate purchase price of preferred shares |  |  | (1,618,509) |  |  |  |  |  |  |  |  | 2,900,000 |  |  |
Investment in preferred stock by outsider |  |  |  |  |  |  |  |  |  |  |  | 1,600,000 |  |  |
Non-cash impairment charge |  |  |  |  |  |  |  |  |  |  |  |  |  | 1,400,000 |
Carrying value of the investment |  |  |  |  |  |  |  |  |  |  |  |  |  | 0 |
Reserve against receivable |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 1,900,000 |

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