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Investment in Subsidiaries - Additional Information (Detail) (USD $)
 1 Months Ended 12 Months Ended 12 Months Ended 12 Months Ended 12 Months Ended
Aug. 10, 2012
Sep. 30, 2012
Sep. 30, 2011
Nov. 26, 2008
Jan. 31, 2011
Preferred Class B and C [Member]
Sep. 30, 2010
Calando Pharmaceuticals, Inc. [Member]
Sep. 30, 2012
Calando Pharmaceuticals, Inc. [Member]
Jan. 31, 2011
Calando Pharmaceuticals, Inc. [Member]
Jun. 23, 2009
Calando Pharmaceuticals, Inc. [Member]
Nov. 26, 2008
Calando Pharmaceuticals, Inc. [Member]
Apr. 17, 2008
Calando Pharmaceuticals, Inc. [Member]
Sep. 30, 2011
Ablaris Therapeutics, Inc. [Member]
Sep. 30, 2012
Ablaris Therapeutics, Inc. [Member]
Sep. 30, 2012
Nanotope, Inc [Member]
Sep. 30, 2012
Leonardo Biosystems Inc [Member]
Schedule of Investments [Line Items]                              
Ownership percentage in subsidiary   100.00%                          
Aggregate investment in subsidiary through equity and debt                     $ 23,200,000        
Unsecured Convertible Promissory Note Agreements       2,500,000           2,500,000          
Investment in Notes offering       200,000           200,000          
Additional investment in Notes offering       600,000           600,000          
Principal amount of note which not converted into shares                 500,000            
Conversion of Notes and accrued interest into share                 2,950            
Issuance and sold of Common Stock 2,260,869         122,000                  
Issuance of warrants           26,400                  
Investment in preferred stock         9,100,000             1,300,000      
Cash investment in subsidiary               1,000,000              
Investment in subsidiary through conversion of intercompany debt               8,100,000              
Amount owed by subsidiary             3,100,000               547,000
Stated percentage of notes and advances             8.00%                
Percentage of outstanding shares             79.00%           64.00% 23.00% 3.00%
Percentage of investment ownership             76.00%           64.00% 19.00%  
Aggregate purchase price of preferred shares     (1,618,509)                 2,900,000      
Investment in preferred stock by outsider                       1,600,000      
Non-cash impairment charge                           1,400,000  
Carrying value of the investment                           0  
Reserve against receivable                           $ 1,900,000