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Investment In Subsidiaries
6 Months Ended
Mar. 31, 2012
Investment In Subsidiaries [Abstract]  
Investment In Subsidiaries

NOTE 3. INVESTMENT IN SUBSIDIARIES

Calando Pharmaceuticals, Inc. (formerly known as Insert Therapeutics, Inc. "Insert")

Calando is a clinical stage RNAi delivery company. On April 17, 2008, Calando merged with and into Insert, with Insert as the surviving company. Prior to the merger, Arrowhead invested an aggregate of $23.2 million in Calando through equity and debt financings. As a condition of the merger, the Preferred Stock of each of Calando and Insert was converted into common stock and the loans were converted to equity. As a result of the merger, shares of Insert common stock were issued to the stockholders of the former Calando, and Insert changed its name to Calando Pharmaceuticals, Inc.

On November 26, 2008, Calando entered into Unsecured Convertible Promissory Note Agreements ("Notes") for $2.5 million with accredited investors and Arrowhead, which invested $200,000 in the Notes offering. Arrowhead subsequently invested an additional $600,000 in the same offering. Except for one Note in the principal amount of $500,000, all Notes and accrued interest were converted into a total of 2,950 shares of Calando Series A Preferred Stock on June 23, 2009. The remaining Note is due November 26, 2013; see Note 4 for further information.

In fiscal 2010, Arrowhead issued 122,000 shares of its Common Stock in exchange for shares of Calando common stock, with several minority stockholders of Calando. In conjunction with this exchange, Arrowhead also issued 26,400 warrants to purchase Arrowhead Common Stock in exchange for warrants to purchase Calando common stock.

In January 2011, Arrowhead invested $9.1 million, through a cash investment of $1.0 million and the conversion of $8.1 million intercompany debt, acquiring newly issued Calando Series B and Series C preferred stock.

As of March 31, 2012, Calando owed to Arrowhead $2,108,483 under a series of 10% simple interest notes and advances. It is expected that these loans will either be repaid or converted to equity in the future. The balance of the notes and advances is eliminated in consolidation.

As of March 31, 2012, Arrowhead owned 79% of the outstanding shares of Calando and 76% on a fully diluted basis.

Ablaris Therapeutics, Inc.

Ablaris was formed and began operations in the first quarter of fiscal 2011, based on the license of certain anti-obesity technology developed at the MD Anderson Cancer Center at the University of Texas. During the year ended September 30, 2011, Ablaris raised $2.9 million in cash, of which $1.3 million was invested by Arrowhead and $1.6 million was invested by outside investors, through the issuance of Series A Preferred stock.

As of March 31, 2012, Arrowhead owned 64% of the outstanding shares of Ablaris and 64% on a fully diluted basis.

Nanotope, Inc.

Nanotope is developing advanced nanomaterials for the treatment of spinal cord injuries, cartilage regeneration and wound healing. As of March 31, 2012, Arrowhead owned 23% of the outstanding shares of Nanotope, and 19% on a fully diluted basis. Arrowhead accounts for its investment in Nanotope using the equity method of accounting. As of March 31, 2012, Nanotope owed to Arrowhead $1.8 million, which Arrowhead has included in other receivables. It is expected that this indebtedness will be repaid or converted to equity.

 

Summarized financial information for Nanotope, Inc. is as follows:

 

     March 31, 2012     September 30, 2011  

Current assets

   $ 27,000      $ 21,000   

Non-current assets 529

     63,000        85,000   

Liabilities

     1,982,000        1,255,000   

Equity

     (1,892,000     (1,149,000

 

     For the three months
ended
    For the three months
ended
    For the six months
ended
    For the six months
ended
 
     March 31, 2012     March 31, 2011     March 31, 2012     March 31, 2011  

Revenue

   $ 0      $ 17,000      $ 0      $ 9,000   

Operating expenses

     254,000        338,000        692,000        457,000   

Net loss

     (279,000     (325,000     (743,000     (448,000

 

     For the six months
ended
    For the six months
ended
 
     March 31, 2012     March 31, 2011  

Cash flows used in operating activities

   $ (560,000   $ (128,000

Cash flows used in investing activities

     (5,000     (20,000

Cash flows provided by financing activities

     563,000        545,000   

Leonardo Biosystems, Inc.

Leonardo is developing a drug-delivery platform technology based on novel methods of designing porous silicon microparticles that selectively accumulate in tumor vasculature. Arrowhead accounts for its investment in Leonardo using the cost method of accounting. As of March 31, 2012, Leonardo owed to Arrowhead $530,000, included in other receivables, which is expected to be repaid or converted to equity. As of March 31, 2012, Arrowhead's ownership interest in Leonardo was 5%.