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Leases - Additional Information (Detail) (USD $)
 1 Months Ended 3 Months Ended 116 Months Ended
Aug. 31, 2012
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2012
Component of Operating Other Cost and Expense [Line Items]        
Rental expense $ 13,000     $ 4,270,000
Lease term 5 years      
Percentage of increase in annual rental cost 3.00%      
Rental expenses include common area maintenance and real estate taxes   13,000    
Utilities costs per month   16,000    
Increase in total monthly expenditures   72,000    
Facility and equipment rent expense   145,000 90,000  
Roche [Member]
        
Component of Operating Other Cost and Expense [Line Items]        
Rental expense   22,000    
Monthly payments under capital lease   $ 21,000