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v3.3.1.900

Consolidated Statement of Stockholders' Equity - USD ($) | Total | Common stock issued @ $4.49 | Common stock issued @ $2.26 | Common stock issued @ $2.12 | Common stock issued @ $1.83 | Preferred stock issued at $1,000 per share | Common stock issued @ $5.86 | Common stock issued @ $18.95 | Common Stock Issued to Galloway | Novartis | Preferred Stock | Preferred Stock Preferred stock issued at $1,000 per share | Common Stock | Common Stock Common stock issued @ $4.49 | Common Stock Common stock issued @ $2.26 | Common Stock Common stock issued @ $2.12 | Common Stock Common stock issued @ $1.83 | Common Stock Common stock issued @ $5.86 | Common Stock Common stock issued @ $18.95 | Common Stock Common Stock Issued to Galloway | Common Stock Novartis | Additional Paid In Capital | Additional Paid In Capital Common stock issued @ $4.49 | Additional Paid In Capital Common stock issued @ $2.26 | Additional Paid In Capital Common stock issued @ $2.12 | Additional Paid In Capital Common stock issued @ $1.83 | Additional Paid In Capital Preferred stock issued at $1,000 per share | Additional Paid In Capital Common stock issued @ $5.86 | Additional Paid In Capital Common stock issued @ $18.95 | Additional Paid In Capital Common Stock Issued to Galloway | Additional Paid In Capital Novartis | Subscriptions Receivable | Accumulated Other Comprehensive Income (loss) | Accumulated Deficit | Noncontrolling Interest
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Beginning Balance Amount at Sep. 30, 2012 | $ 8,808,909 |  |  |  |  |  |  |  |  |  |  |  | $ 108,354 |  |  |  |  |  |  |  |  | $ 145,917,968 |  |  |  |  |  |  |  |  |  | $ (1,016,000) |  | $ (134,997,680) | $ (1,203,733)
Beginning Balance Shares at Sep. 30, 2012 |  |  |  |  |  |  |  |  |  |  |  |  | 13,579,185 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Exercise of warrants, Amount | 2,054,599 |  |  |  |  |  |  |  |  |  |  |  | $ 1,183 |  |  |  |  |  |  |  |  | 2,053,416 |  |  |  |  |  |  |  |  |  |  |  |  |
Exercise of warrants |  |  |  |  |  |  |  |  |  |  |  |  | 1,182,451 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock options exercised, Amount | 2,579 |  |  |  |  |  |  |  |  |  |  |  | $ 1 |  |  |  |  |  |  |  |  | 2,578 |  |  |  |  |  |  |  |  |  |  |  |  |
Stock options exercised |  |  |  |  |  |  |  |  |  |  |  |  | 675 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock-based compensation | 1,536,271 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 1,536,271 |  |  |  |  |  |  |  |  |  |  |  |  |
Subscription payment | 16,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 16,000 |  |  |
Subscription reversal, Amount |  |  |  |  |  |  |  |  |  |  |  |  | $ (2,674) |  |  |  |  |  |  |  |  | (997,326) |  |  |  |  |  |  |  |  |  | $ 1,000,000 |  |  |
Subscription reversal |  |  |  |  |  |  |  |  |  |  |  |  | (267,444) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock issuances |  | $ 986,049 | $ 3,816,468 | $ 3,256,859 | $ 25,459,499 | $ 9,900,000 |  |  |  |  |  | $ 10 |  | $ 240 | $ 1,825 | $ 1,667 | $ 14,263 |  |  |  |  |  | $ 985,809 | $ 3,814,643 | $ 3,255,192 | $ 25,445,236 | $ 9,899,990 |  |  |  |  |  |  |  |
Stock issuances, Shares |  |  |  |  |  |  |  |  |  |  |  | 9,900 |  | 239,894 | 1,825,079 | 1,667,051 | 14,262,553 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Establish and settlements related to derivative liability | 1,600,989 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 1,600,989 |  |  |  |  |  |  |  |  |  |  |  |  |
Net loss | (31,703,433) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | (31,143,289) | (560,144)
Ending Balance Amount at Sep. 30, 2013 | 25,734,789 |  |  |  |  |  |  |  |  |  | $ 10 |  | $ 124,859 |  |  |  |  |  |  |  |  | 193,514,766 |  |  |  |  |  |  |  |  |  |  |  | (166,140,969) | (1,763,877)
Ending Balance Shares at Sep. 30, 2013 |  |  |  |  |  |  |  |  |  |  | 9,900 |  | 32,489,444 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Exercise of warrants, Amount | 10,148,044 |  |  |  |  |  |  |  |  |  |  |  | $ 2,911 |  |  |  |  |  |  |  |  | 10,145,133 |  |  |  |  |  |  |  |  |  |  |  |  |
Exercise of warrants |  |  |  |  |  |  |  |  |  |  |  |  | 2,911,919 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock options exercised, Amount | 2,730,000 |  |  |  |  |  |  |  |  |  |  |  | $ 455 |  |  |  |  |  |  |  |  | 2,729,545 |  |  |  |  |  |  |  |  |  |  |  |  |
Stock options exercised |  |  |  |  |  |  |  |  |  |  |  |  | 454,863 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock-based compensation | 5,696,173 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 5,696,173 |  |  |  |  |  |  |  |  |  |  |  |  |
Stock issuances |  |  |  |  |  | $ 46,000,000 | $ 14,060,112 | $ 112,581,559 | $ 500,000 |  |  | $ 46 |  |  |  |  |  | $ 3,072 | $ 6,325 | $ 132 |  |  |  |  |  |  | $ 45,999,954 | $ 14,057,040 | $ 112,575,234 | $ 499,868 |  |  |  |  |
Stock issuances, Shares |  |  |  |  |  |  |  |  |  |  |  | 46,000 |  |  |  |  |  | 3,071,672 | 6,325,000 | 131,579 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Establish and settlements related to derivative liability | 5,956,079 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 5,956,079 |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred stock converted to common stock, Amount |  |  |  |  |  |  |  |  |  |  | $ (38) |  | $ 9,272 |  |  |  |  |  |  |  |  | (9,234) |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred stock converted to common stock, Shares |  |  |  |  |  |  |  |  |  |  | (37,600) |  | 9,272,459 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deconsolidation of Calando Pharmaceuticals, Inc. | 1,303,911 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 1,303,911
Net loss | (58,725,412) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | (58,630,190) | (95,222)
Ending Balance Amount at Sep. 30, 2014 | 165,985,255 |  |  |  |  |  |  |  |  |  | $ 18 |  | $ 147,026 |  |  |  |  |  |  |  |  | 391,164,558 |  |  |  |  |  |  |  |  |  |  |  | (224,771,159) | (555,188)
Ending Balance Shares at Sep. 30, 2014 |  |  |  |  |  |  |  |  |  |  | 18,300 |  | 54,656,936 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Exercise of warrants, Amount | 401,876 |  |  |  |  |  |  |  |  |  |  |  | $ 81 |  |  |  |  |  |  |  |  | 401,795 |  |  |  |  |  |  |  |  |  |  |  |  |
Exercise of warrants |  |  |  |  |  |  |  |  |  |  |  |  | 79,828 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock options exercised, Amount | $ 101,870 |  |  |  |  |  |  |  |  |  |  |  | $ 29 |  |  |  |  |  |  |  |  | 101,841 |  |  |  |  |  |  |  |  |  |  |  |  |
Stock options exercised | 28,758 |  |  |  |  |  |  |  |  |  |  |  | 28,758 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock-based compensation | $ 10,232,897 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 10,232,897 |  |  |  |  |  |  |  |  |  |  |  |  |
Exercise of exchange rights, Amount | 3,072 |  |  |  |  |  |  |  |  |  |  |  | $ 5 |  |  |  |  |  |  |  |  | 3,067 |  |  |  |  |  |  |  |  |  |  |  |  |
Exercise of exchange rights, Shares |  |  |  |  |  |  |  |  |  |  |  |  | 5,250 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred stock converted to common stock, Amount |  |  |  |  |  |  |  |  |  |  | $ (2) |  | $ 1,316 |  |  |  |  |  |  |  |  | (1,314) |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred stock converted to common stock, Shares |  |  |  |  |  |  |  |  |  |  | (2,648) |  | 1,316,215 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock-RSU vesting, Amount | (26,029) |  |  |  |  |  |  |  |  |  |  |  | $ 136 |  |  |  |  |  |  |  |  | (26,165) |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock-RSU vesting, Shares |  |  |  |  |  |  |  |  |  |  |  |  | 136,307 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock issuances |  |  |  |  |  |  |  |  |  | $ 25,000,000 |  |  |  |  |  |  |  |  |  |  | $ 3,321 |  |  |  |  |  |  |  |  |  | $ 24,996,679 |  |  |  |
Stock issuances, Shares |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 3,321,383 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Foreign Currency Translation Adjustments | (136,425) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ (136,425) |  |
Net loss | (91,940,882) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | (91,940,882) |
Ending Balance Amount at Sep. 30, 2015 | $ 109,621,634 |  |  |  |  |  |  |  |  |  | $ 16 |  | $ 151,914 |  |  |  |  |  |  |  |  | $ 426,873,358 |  |  |  |  |  |  |  |  |  |  | $ (136,425) | $ (316,712,041) | $ (555,188)
Ending Balance Shares at Sep. 30, 2015 |  |  |  |  |  |  |  |  |  |  | 15,652 |  | 59,544,677 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

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