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Collaboration and License Agreements - Amgen, Inc - Additional Information (Detail) |  |  |  |  | 1 Months Ended | 12 Months Ended
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Nov. 18, 2016 USD ($) shares | Sep. 30, 2016 Tranche $ / shares shares | Sep. 29, 2016 USD ($) shares | Sep. 28, 2016 USD ($) Agreement | Nov. 30, 2016 USD ($) | Sep. 30, 2016 USD ($) Tranche $ / shares shares | Aug. 31, 2016 USD ($) | Sep. 30, 2016 USD ($) Tranche $ / shares shares | Sep. 30, 2014 USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Proceeds from the issuance of common stock |  |  |  |  |  |  | $ 43,200,000 | $ 52,231,433 | $ 172,641,671
Amgen |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Stock issued, price per share | $ / shares |  | $ 7.16 |  |  |  | $ 7.16 |  | $ 7.16 |
Collaboration and License agreements | Amgen |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Agreement date |  | Sep. 28, 2016 |  |  |  |  |  |  |
Number of agreements | Agreement |  |  |  | 2 |  |  |  |  |
First Collaboration and License Agreement | Amgen |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Additional amount of common stock shares agreed to sell upon exercise of option |  |  |  | $ 5,000,000 |  |  |  |  |
Number of trading days, used to calculate share price of Common Stock, surrounding option exercise date |  |  |  | 30 days |  |  |  |  |
Cash received as due under collaboration agreement |  |  |  |  |  | $ 5,000,000 |  |  |
Collaboration and License agreements |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Cash to be received as due under collaboration agreement |  |  |  | $ 35,000,000 |  |  |  |  |
Collaboration and License agreements | Amgen |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Proceeds from the issuance of common stock |  |  |  | 21,500,000 |  |  |  |  |
Collaboration and License agreements | Maximum |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Option payments, and development, regulatory and sales milestone payments. |  |  |  | $ 617,000,000 |  |  |  |  |
Second Collaboration and License Agreement | Amgen | Subsequent Event |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Cash received as due under collaboration agreement | $ 30,000,000 |  |  |  | $ 30,000,000 |  |  |  |
Common Stock Purchase Agreement | Amgen |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Agreement date |  | Sep. 28, 2016 |  |  |  |  |  |  |
Shares issued | shares |  | 3,002,793 |  |  |  | 3,002,793 |  | 3,002,793 |
Stock issued, price per share | $ / shares |  | $ 7.16 |  |  |  | $ 7.16 |  | $ 7.16 |
Number of tranches to deliver shares as per agreement | Tranche |  | 2 |  |  |  | 2 |  | 2 |
Proceeds from the issuance of common stock |  |  |  |  |  |  |  | $ 9,000,000 |
Common Stock Purchase Agreement | Amgen | NASDAQ |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Number of trading days, used to calculate weighted average price of Common Stock, listed in stock market |  | 30 days |  |  |  |  |  |  |
Common Stock Purchase Agreement | Amgen | Subsequent Event |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Proceeds from the issuance of common stock | $ 12,500,000 |  |  |  |  |  |  |  |
Common Stock Purchase Agreement Tranche 1 | Amgen |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Shares issued | shares |  |  | 1,256,983 |  |  |  |  |  |
Proceeds from the issuance of common stock |  |  | $ 9,000,000 |  |  |  |  |  |
Common Stock Purchase Agreement Tranche 2 | Amgen | Subsequent Event |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |
Shares issued | shares | 1,745,810 |  |  |  |  |  |  |  |
Proceeds from the issuance of common stock | $ 12,500,000 |  |  |  |  |  |  |  |

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