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Fair Value Measurements - Additional Information (Detail) | 3 Months Ended | 12 Months Ended |  |  |  |
--- | --- | --- | --- | --- | --- | ---
Dec. 31, 2015 USD ($) shares | Dec. 31, 2014 USD ($) | Sep. 30, 2011 shares | Sep. 30, 2015 USD ($) | Jan. 31, 2013 shares | Dec. 31, 2012 shares | Jun. 30, 2010 shares
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |
Short term investments | $ | $ 14,431,498 |  |  | $ 17,539,902 |  |  |
Fair value of investment | $ | $ 14,271,893 |  |  | $ 17,234,960 |  |  |
Warrants outstanding | 1,466,437 |  |  |  |  |  |
Non-cash gain (loss) from change in fair value of the derivative liability | $ | $ (21,574) | $ 2,179,651 |  |  |  |  |
Ablaris Therapeutics |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |
Warrants outstanding | 500,000 |  |  |  |  |  |
Non-cash gain (loss) from change in fair value of the derivative liability | $ | $ (1,950) | $ 202,491 |  |  |  |  |
Duration of exchange rights | 7 years |  |  |  |  |  |
Exchange right convertible conversion ratio for first year | 0.06 |  |  |  |  |  |
Exchange right convertible conversion ratio for second year | 0.04 |  |  |  |  |  |
Exchange right convertible conversion ratio for third year | 0.03 |  |  |  |  |  |
Exchange right convertible conversion ratio for fourth year | 0.02 |  |  |  |  |  |
Exchange right convertible conversion ratio for fifth year and beyond | 0.01 |  |  |  |  |  |
Number of exchange right sold |  |  | 675,000 |  |  |  |
2010 Warrants |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |
Warrants issued to acquire Common Stock |  |  |  |  |  |  | 329,649
Warrants expired | 24,324 |  |  |  |  |  |
2012 Warrants |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |
Warrants issued to acquire Common Stock |  |  |  |  |  | 912,543 |
Warrants outstanding | 265,161 |  |  |  |  |  |
2013 Warrants |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |
Warrants issued to acquire Common Stock |  |  |  |  | 833,530 |  |
Warrants outstanding | 12,123 |  |  |  |  |  |

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