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Fair Value Measurements - Additional Information (Detail)
 3 Months Ended 12 Months Ended
Dec. 31, 2016
USD ($)
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Dec. 31, 2015
USD ($)
Sep. 30, 2011
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Jan. 31, 2013
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Dec. 31, 2012
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Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]          
Warrants outstanding 527,181        
Non-cash gain (loss) from change in fair value of the derivative liability | $ $ 1,454,831 $ (21,574)      
Ablaris Therapeutics          
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]          
Warrants outstanding 500,000        
Non-cash gain (loss) from change in fair value of the derivative liability | $ $ 29,000 $ (1,950)      
Duration of exchange rights 7 years        
Exchange right convertible conversion ratio 0.01        
Number of exchange right sold     675,000    
2012 Warrants          
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]          
Warrants issued to acquire Common Stock         912,543
Warrants outstanding 265,161        
2013 Warrants          
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]          
Warrants issued to acquire Common Stock       833,530  
Warrants outstanding 12,123